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AB327121

Anti-BCL11B Antibody [CL6426]

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Mouse Monoclonal Ctip2 antibody. Suitable for WB, IHC-P and reacts with Human, Mouse samples. Immunogen corresponding to Synthetic Peptide within Human BCL11B.

View Alternative Names

CTIP2, RIT1, BCL11B, B-cell lymphoma/leukemia 11B, BCL-11B, B-cell CLL/lymphoma 11B, COUP-TF-interacting protein 2, Radiation-induced tumor suppressor gene 1 protein, hRit1

8 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BCL11B Antibody [CL6426] (AB327121)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BCL11B Antibody [CL6426] (AB327121)

Immunohistochemical staining of human tonsil using ab327121 at 1 : 500–1 : 1000 dilution, showing moderate to strong nuclear positivity, mainly in non - germinal center cells.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BCL11B Antibody [CL6426] (AB327121)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BCL11B Antibody [CL6426] (AB327121)

Immunohistochemistry analysis in human tonsil and pancreas tissues using ab327121 at 1 : 500–1 : 1000 dilution. Corresponding BCL11B RNA-seq data are presented for the same tissues.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BCL11B Antibody [CL6426] (AB327121)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BCL11B Antibody [CL6426] (AB327121)

Immunohistochemical staining of human skin using ab327121 at 1 : 500–1 : 1000 dilution, showing moderate to strong nuclear positivity in dermal cells.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BCL11B Antibody [CL6426] (AB327121)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BCL11B Antibody [CL6426] (AB327121)

Immunohistochemical staining of mouse hippocampus using ab327121 at 1 : 500–1 : 1000 dilution, showing strong nuclear positivity in neurons in CA1 pyramidal layer.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BCL11B Antibody [CL6426] (AB327121)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BCL11B Antibody [CL6426] (AB327121)

Immunohistochemical staining of mouse cerebral cortex using ab327121 at 1 : 500–1 : 1000 dilution, showing moderate to strong nuclear positivity in neurons, mainly in layers 5-6.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BCL11B Antibody [CL6426] (AB327121)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BCL11B Antibody [CL6426] (AB327121)

Immunohistochemical staining of mouse hippocampus using ab327121 at 1 : 500–1 : 1000 dilution, showing strong nuclear positivity in neurons in the granular cell layer of dentate gyrus.

Western blot - Anti-BCL11B Antibody [CL6426] (AB327121)
  • WB

Supplier Data

Western blot - Anti-BCL11B Antibody [CL6426] (AB327121)

Western blot analysis in human cerebral cortex tissue using ab327121 at 1 µg/ml.

All lanes:

Western blot - Anti-BCL11B Antibody [CL6426] (ab327121)

All lanes:

Human cerebral cortex tissue

Predicted band size: 95.52 kDa

false

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BCL11B Antibody [CL6426] (AB327121)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BCL11B Antibody [CL6426] (AB327121)

Immunohistochemical staining of human pancreas using ab327121 at 1 : 500–1 : 1000 dilution, showing no positivity in exocrine glandular cells as expected.

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

CL6426

Isotype

IgG1

Carrier free

No

Reacts with

Human, Mouse

Applications

IHC-P, WB

applications

Immunogen

Synthetic Peptide within Human BCL11B.

Q9C0K0

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1 µg/mL", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/500 - 1/1000", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval before commencing with IHC staining protocol." }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1 µg/mL", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/500 - 1/1000", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval before commencing with IHC staining protocol." } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
-20°C
Appropriate long-term storage conditions
-20°C
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Key regulator of both differentiation and survival of T-lymphocytes during thymocyte development in mammals. Essential in controlling the responsiveness of hematopoietic stem cells to chemotactic signals by modulating the expression of the receptors CCR7 and CCR9, which direct the movement of progenitor cells from the bone marrow to the thymus (PubMed : 27959755). Is a regulator of IL2 promoter and enhances IL2 expression in activated CD4(+) T-lymphocytes (PubMed : 16809611). Tumor-suppressor that represses transcription through direct, TFCOUP2-independent binding to a GC-rich response element (By similarity). May also function in the P53-signaling pathway (By similarity).
See full target information BCL11B
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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