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AB245422

Anti-BCOR antibody

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(1 Publication)

Rabbit Polyclonal BCOR antibody. Suitable for IP and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human BCOR aa 1-100.

View Alternative Names

KIAA1575, BCOR, BCL-6 corepressor, BCoR

1 Images
Immunoprecipitation - Anti-BCOR antibody (AB245422)
  • IP

Supplier Data

Immunoprecipitation - Anti-BCOR antibody (AB245422)

BCOR was immunoprecipitated from HeLa (human epithelial cell line from cervix adenocarcinoma) whole cell lysate (1 mg for IP, 20% of IP loaded) with ab245422 at 6 μg/mg lysate. Western blot was performed from the immunoprecipitate using an alternative anti-BCOR antibody at 1 μg/ml.

Lane 1 : ab245422 (lot 1) IP in HeLa whole cell lysate.

Lane 2 : ab245422 (lot 2) IP in HeLa whole cell lysate.

Lane 3 : Control IgG IP in HeLa whole cell lysate.

Detection : Chemiluminescence with exposure time of 3 minutes.

All lanes:

Immunoprecipitation - Anti-BCOR antibody (ab245422)

Predicted band size: 192 kDa

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Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IP

applications

Immunogen

Synthetic Peptide within Human BCOR aa 1-100. The exact immunogen used to generate this antibody is proprietary information.

Q6W2J9

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "testedAndGuaranteed", "IP-species-dilution-info": "2-10 µg/mg of lysate", "IP-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Purification notes
ab245422 was affinity purified using an epitope specific to BCOR immobilized on solid support.
Storage buffer
pH: 7 - 8 Preservative: 0.09% Sodium azide Constituents: Tris citrate/phosphate
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6 and MLLT3. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Involved in the repression of TFAP2A; impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells; the function implies inhibition of methylation on histone H3 'Lys-4' (H3K4me3) and 'Lys-36' (H3K36me2).
See full target information BCOR
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Histology and histopathology 38:1109-1118 PubMed36916695

2023

Women with psychotic episodes during pregnancy show increased markers of placental damage with Tenney-Parker changes.

Applications

Unspecified application

Species

Unspecified reactive species

Miguel A Ortega,Oscar Fraile-Martinez,Cielo García-Montero,Sonia Rodriguez-Martín,Rosa M Funes Moñux,Leonel Pekarek,Coral Bravo,Juan A De Leon-Luis,Miguel A Saez,Luis G Guijarro,Guillermo Lahera,Jorge Monserrat,Roberto Rodriguez-Jimenez,Jose V Saz,Julia Bujan,Natalio García-Honduvilla,Melchor Alvarez-Mon,Miguel Angel Alvarez-Mon
View all publications
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Product promise

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