AB19270

Anti-BD-3 antibody

Name: Anti-BD-3 antibody (ab19270) | Abcam
Brand: Abcam Limited
SKU: AB19270
Price: 525 USD
Availability: InStock
Rating: 4 (1 reviews)

(1 Review)

(12 Publications)

Rabbit Polyclonal D103A antibody. Suitable for WB, ICC/IF and reacts with Human samples. Cited in 12 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human DEFB103A.

View Alternative Names

BD3, DEFB103, DEFB3, DEFB103B, DEFB103A, Beta-defensin 103, Beta-defensin 3, Defensin-like protein, BD-3, DEFB-3, HBD3, hBD-3

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

ICC/IF, WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Human DEFB103A.

P81534

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein A

Storage buffer

pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed.

See full target information DEFB103A

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Publications (12)

Recent publications for all applications. Explore the full list and refine your search

Clinical, cosmetic and investigational dermatology 18:459-473 PubMed40046939

2025

Influence of Injectable Hyaluronic Gel System on Skin Microbiota, Skin Defense Mechanisms and Integrity (Ex vivo Study).

Applications

Unspecified application

Species

Unspecified reactive species

Aleksei Y Prokopov,Zarema I Gazitaeva,Anna N Sidorina,Laurent Peno-Mazzarino,Nikita Radionov,Anna O Drobintseva,Igor M Kvetnoy

Polish journal of veterinary sciences 25:237-248 PubMed35861957

2022

Expression of anti-inflammatory markers IL-2, IL-10, TGF-β1, βDEF-2, βDEF-3 and Cathelicidin LL37 in dairy cattle milk with different health status of the udder.

Applications

Unspecified application

Species

Unspecified reactive species

K Šerstņova,M Pilmane,Z Vitenberga-Verza,I Melderis,Ł Gontar,M Kochański,A Drutowska,G Maróti,B Prieto-Simón

Aging cell 21:e13532 PubMed34905649

2021

Growth differentiation factor 11 accelerates liver senescence through the inhibition of autophagy.

Applications

Unspecified application

Species

Unspecified reactive species

Jian Sun,Ying Li,Xiao Yang,Wei Dong,Jiankun Yang,Qi Hu,Cuntai Zhang,Haoshu Fang,Anding Liu

Frontiers in bioengineering and biotechnology 9:631191 PubMed33585435

2021

Gold Nanoparticles Combined Human β-Defensin 3 Gene-Modified Human Periodontal Ligament Cells Alleviate Periodontal Destruction the p38 MAPK Pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Lingjun Li,Yangheng Zhang,Min Wang,Jing Zhou,Qian Zhang,Wenrong Yang,Yanfen Li,Fuhua Yan

International journal of oral science 12:13 PubMed32350241

2020

Human β-defensin 3 gene modification promotes the osteogenic differentiation of human periodontal ligament cells and bone repair in periodontitis.

Applications

Unspecified application

Species

Unspecified reactive species

Lingjun Li,Han Jiang,Rixin Chen,Jing Zhou,Yin Xiao,Yangheng Zhang,Fuhua Yan

Journal of virology 94: PubMed31996426

2020

An Alphaherpesvirus Exploits Antimicrobial β-Defensins To Initiate Respiratory Tract Infection.

Applications

Unspecified application

Species

Unspecified reactive species

Jolien Van Cleemput,Katrien C K Poelaert,Kathlyn Laval,Nathalie Vanderheijden,Maarten Dhaenens,Simon Daled,Filip Boyen,Frank Pasmans,Hans J Nauwynck

Biochimica et biophysica acta. Molecular and cell 1865:158673 PubMed32092464

2020

Skin of atopic dermatitis patients shows disturbed β-glucocerebrosidase and acid sphingomyelinase activity that relates to changes in stratum corneum lipid composition.

Applications

Unspecified application

Species

Unspecified reactive species

Daphne E C Boer,Jeroen van Smeden,Hanin Al-Khakany,Elizaveta Melnik,Rianne van Dijk,Samira Absalah,Rob J Vreeken,Caroline C P Haenen,Adriana P M Lavrijsen,Herman S Overkleeft,Johannes M F G Aerts,Joke A Bouwstra

Cell metabolism 28:557-572.e6 PubMed30017352

2018

Gut Microbiota-Stimulated Innate Lymphoid Cells Support β-Defensin 14 Expression in Pancreatic Endocrine Cells, Preventing Autoimmune Diabetes.

Applications

Unspecified application

Species

Unspecified reactive species

Michela Miani,Julie Le Naour,Emmanuelle Waeckel-Enée,Subash Chand Verma,Marjolène Straube,Patrick Emond,Bernhard Ryffel,Peter van Endert,Harry Sokol,Julien Diana

Molecular medicine reports 16:7459-7467 PubMed28944821

2017

Transplantation of periodontal ligament cell sheets expressing human β‑defensin‑3 promotes anti‑inflammation in a canine model of periodontitis.

Applications

Unspecified application

Species

Unspecified reactive species

Minwen Zhu,Bo Miao,Jianhua Zhu,Haiyan Wang,Zengtong Zhou

Molecular medicine reports 16:2455-2460 PubMed28677765

2017

Expression and antimicrobial character of cells transfected with human β‑defensin‑3 against periodontitis‑associated microbiota in vitro.

Applications

Unspecified application

Species

Unspecified reactive species

Minwen Zhu,Bo Miao,Jianhua Zhu,Haiyan Wang,Zengtong Zhou

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-BD-3 antibody

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (12)

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