Anti-beta 2 Defensin/BD-2 antibody
4
(2 Reviews)
|
(10 Publications)
Goat Polyclonal DFB4A antibody. Suitable for WB, sELISA and reacts with Human, Recombinant full length protein - Human samples. Cited in 10 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human DEFB4A.
View Alternative Names
DEFB102, DEFB2, DEFB4, DEFB4B, DEFB4A, Defensin beta 4A, Beta-defensin 2, Skin-antimicrobial peptide 1, BD-2, hBD-2, SAP1
- sELISA
Supplier Data
Sandwich ELISA - Anti-beta 2 Defensin/BD-2 antibody (AB9871)
Sandwich ELISA : To detect Human BD-2 by sandwich ELISA (using 100 µL/well antibody solution) a concentration of 0.5-2.0 µg/mL of beta-2 Defensin Polyclonal Antibody is required. This antigen affinity purified antibody, in conjunction with a beta-2 Defensin Polyclonal Antibody, Biotin as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human BD-2.
Reactivity data
Product details
Properties and storage information
Form
Reconstitution
Purification technique
Storage buffer
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
Beta 2 defensin serves as a critical component of host defense mechanisms. It not only shows antimicrobial properties but also influences inflammatory processes. BD-2 interacts with immune cells recruiting and activating them for enhanced defense response. Presently there is no evidence of beta 2 defensin being part of a larger protein complex focusing its function on immediate immune response and cellular signaling in areas it is expressed.
Pathways
Beta 2 defensin engages in critical pathways of immune protection. It is part of the toll-like receptor signaling pathway and engages the NF-kB pathway. These pathways are essential for activating immune responses when pathogens are recognized. Additionally beta 2 defensin interacts with other defensins and related antimicrobial peptides to mount an effective immune response coordinating with various cytokines and chemokines to balance protective actions.
Product protocols
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Target data
Publications (10)
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Microbiome 11:227 PubMed37849006
2023
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iScience 26:106483 PubMed37096035
2023
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Frontiers in veterinary science 9:925701 PubMed35812842
2022
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Stem cells translational medicine 9:235-249 PubMed31702119
2019
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The Journal of investigative dermatology 140:415-424.e10 PubMed31344386
2019
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Scientific reports 8:10044 PubMed29968819
2018
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The Journal of investigative dermatology 130:2611-20 PubMed20631729
2010
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Respiratory medicine 103:201-8 PubMed18980836
2008
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Thorax 64:144-9 PubMed18852155
2008
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Clinical and experimental immunology 131:90-101 PubMed12519391
2003
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Product promise
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