Anti-beta Amyloid 1-42 antibody [mOC64] - BSA and Azide free

This antibody was developed as part of a collaboration between Abcam and Professor Charles Glabe, UC Irvine. ab201060 recognizes a conformation-dependent, aggregation-selective epitope of beta amyloid. mOC64 immunoreactivity maps to residues 3-6 (EFRH) of Aß, and preferentially binds to SDS-resistant oligomers over monomer on Western blots (Hatami et al 2014, PMID: 25281743). The epitope is insensitive to thermal denaturation (Hatami et al 2014, PMID: 25281743). It does not recognize pyproglytaminylated Aß at position 3 (Aß3(pE)-42) (Nussbaum et al. 2012, PMID: 22660329). For further information on the immunogen, please refer to Hatami et al 2014, PMID: 25281743 and Kayed et al. 2007, PMID: 17897471.

ab271968 is the carrier-free version of ab201060.

Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

This product is a recombinant monoclonal antibody, which offers several advantages including:

• - High batch-to-batch consistency and reproducibility
• - Improved sensitivity and specificity
• - Long-term security of supply
• - Animal-free batch production

For more information, read more on recombinant antibodies.

Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. The carrier-free buffer and high concentration allow for increased conjugation efficiency.

This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.

Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

This product is compatible with the Maxpar^® Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar^® is a trademark of Fluidigm Canada Inc.