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AB45413

Anti-BFL-1/GRS antibody

2

(2 Reviews)

|

(11 Publications)

Rabbit Polyclonal BFL-1/GRS antibody. Suitable for ICC, WB, IHC-P and reacts with Mouse, Human samples. Cited in 11 publications. Immunogen corresponding to Synthetic Peptide within Human BCL2A1.

View Alternative Names

BCL2L5, BFL1, GRS, HBPA1, BCL2A1, Bcl-2-related protein A1, Bcl-2-like protein 5, Hemopoietic-specific early response protein, Protein BFL-1, Protein GRS, Bcl2-L-5

3 Images
Immunocytochemistry - Anti-BFL-1/GRS antibody (AB45413)
  • ICC

Unknown

Immunocytochemistry - Anti-BFL-1/GRS antibody (AB45413)

Immunofluorescence of Bfl-1 in Mouse Kidney cells using ab45413 at 20 ug/ml.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BFL-1/GRS antibody (AB45413)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BFL-1/GRS antibody (AB45413)

ab45413 at 10μg/ml staining BFL-1/GRS in mouse kidney tissue by IHC

Western blot - Anti-BFL-1/GRS antibody (AB45413)
  • WB

Supplier Data

Western blot - Anti-BFL-1/GRS antibody (AB45413)

All lanes:

Western blot - Anti-BFL-1/GRS antibody (ab45413) at 1 µg/mL

Lane 1:

Human kidney tissue lysate

Lane 2:

Human lung tissue lysate

Predicted band size: 20 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse, Human

Applications

ICC, WB, IHC-P

applications

Immunogen

Synthetic Peptide within Human BCL2A1. The exact immunogen used to generate this antibody is proprietary information.

Q16548

Specificity

This antibody is specific for Bcl2A1 / GRS.

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICC" : {"fullname" : "Immunocytochemistry", "shortname":"ICC"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ICC-species-checked": "guaranteed", "ICC-species-dilution-info": "", "ICC-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.5-1 µg/mL", "WB-species-notes": "<p><strong>WB suitable for Human samples only</strong></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Mouse": { "ICC-species-checked": "testedAndGuaranteed", "ICC-species-dilution-info": "", "ICC-species-notes": "<p><strong>ICC suitable for Mouse samples only</strong></p>", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "10-20 µg/mL", "IHCP-species-notes": "<p><strong>IHC-P suitable for Mouse samples only</strong></p>" } } }

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Target data

Retards apoptosis induced by IL-3 deprivation. May function in the response of hemopoietic cells to external signals and in maintaining endothelial survival during infection (By similarity). Can inhibit apoptosis induced by serum starvation in the mammary epithelial cell line HC11 (By similarity).
See full target information BCL2A1

Publications (11)

Recent publications for all applications. Explore the full list and refine your search

Cell death and differentiation 32:1153-1166 PubMed39994353

2025

Collaborative orchestration of BH3-only proteins governs Bak/Bax-dependent hepatocyte apoptosis under antiapoptotic protein-deficiency in mice.

Applications

Unspecified application

Species

Unspecified reactive species

Shinnosuke Kudo,Hayato Hikita,Yoshinobu Saito,Kazuhiro Murai,Takahiro Kodama,Tomohide Tatsumi,Tetsuo Takehara

Haematologica 109:186-199 PubMed37534528

2024

Hypomethylating agent decitabine sensitizes diffuse large B-cell lymphoma to venetoclax.

Applications

Unspecified application

Species

Unspecified reactive species

Fen Zhu,Jennifer L Crombie,Wei Ni,Nguyet-Minh Hoang,Swati Garg,Liam Hackett,Stephen J F Chong,Mary C Collins,Lixin Rui,James Griffin,Matthew S Davids

Nature communications 13:7923 PubMed36564381

2022

Targeting anti-apoptotic pathways eliminates senescent melanocytes and leads to nevi regression.

Applications

Unspecified application

Species

Unspecified reactive species

Jaskaren Kohli,Chen Ge,Eleni Fitsiou,Miriam Doepner,Simone M Brandenburg,William J Faller,Todd W Ridky,Marco Demaria

Cancers 13: PubMed34572804

2021

The Stress-Inducible BCL2A1 Is Required for Ovarian Cancer Metastatic Progression in the Peritoneal Microenvironment.

Applications

Unspecified application

Species

Unspecified reactive species

Rui Liang,Mingo M H Yung,Fangfang He,Peili Jiao,Karen K L Chan,Hextan Y S Ngan,David W Chan

Annals of translational medicine 9:852 PubMed34164486

2021

MicroRNA-664a-3p inhibits the proliferation of ovarian granulosa cells in polycystic ovary syndrome and promotes apoptosis by targeting BCL2A1.

Applications

Unspecified application

Species

Unspecified reactive species

Min He,Ganghong Mao,Yungai Xiang,Pengfen Li,Yuanyuan Wu,Dongmei Zhao,Tan Li

Frontiers in genetics 12:609754 PubMed33603773

2021

Transcriptomic Signatures and Functional Network Analysis of Chronic Rhinosinusitis With Nasal Polyps.

Applications

Unspecified application

Species

Unspecified reactive species

Yun Hao,Yan Zhao,Ping Wang,Kun Du,Ying Li,Zhen Yang,Xiangdong Wang,Luo Zhang

Leukemia & lymphoma 62:1129-1135 PubMed33327833

2020

Expression of BCL2 alternative proteins and association with outcome in CLL patients treated with venetoclax.

Applications

Unspecified application

Species

Unspecified reactive species

Mario L Marques-Piubelli,Ellen J Schlette,Joseph D Khoury,Fateeha Furqan,Francisco Vega,Luisa M Solis Soto,Ignacio I Wistuba,William G Wierda,Marina Konopleva,Alessandra Ferrajoli,Paolo Strati

International journal of oncology 53:1027-1042 PubMed30015835

2018

Fordin: A novel type I ribosome inactivating protein from Vernicia fordii modulates multiple signaling cascades leading to anti-invasive and pro-apoptotic effects in cancer cells in vitro.

Applications

Unspecified application

Species

Unspecified reactive species

Weili Lu,Yingji Mao,Xue Chen,Jun Ni,Rui Zhang,Yuting Wang,Jun Wang,Lifang Wu

The international journal of biochemistry & cell b 101:1-11 PubMed29727715

2018

MicroRNA-326 aggravates acute lung injury in septic shock by mediating the NF-κB signaling pathway.

Applications

WB, IHC-P

Species

Mouse, Mouse

Chun-Ting Wu,Yan Huang,Zhen-Ye Pei,Xin Xi,Guang-Fa Zhu

Biochemical and biophysical research communications 417:582-7 PubMed22178074

2011

SS-A/Ro52 promotes apoptosis by regulating Bcl-2 production.

Applications

WB

Species

Human

Siti Nur Aisyah Jauharoh,Jun Saegusa,Takeshi Sugimoto,Bambang Ardianto,Shimpei Kasagi,Daisuke Sugiyama,Chiyo Kurimoto,Osamu Tokuno,Yuji Nakamachi,Shunichi Kumagai,Seiji Kawano
View all publications

Product promise

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