Rabbit Polyclonal BGT-1 antibody. Suitable for WB and reacts with Human, Mouse, Rat samples. Cited in 2 publications. Immunogen corresponding to Synthetic Peptide within Human SLC6A12 aa 500-600.
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Publications
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- Communications biology 3:2462020Cells grown in three-dimensional spheroids mirror in vivo metabolic response of epithelial cells.Applications:Unspecified applicationReactive species:Unspecified reactive speciesSimon Lagies et. al.PubMed 32427948
- Mucosal immunology 12:531-5442018Slc6a13 deficiency promotes Th17 responses during intestinal bacterial infection.Applications:Unspecified applicationReactive species:Unspecified reactive speciesWenkai Ren,Yuexia Liao,Xueyan Ding,Ye Jiang,Jiameng Yan,Yaoyao Xia,Bie Tan,Zhijie Lin,Jielin Duan,Xinming Jia,Guan Yang,Jinping Deng,Congrui Zhu,Philip R Hardwidge,Junxia Li,Guoqiang Zhu,Yulong YinPubMed 30523310
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.2
Preservative: 0.097% Sodium azide
Constituents: 99% PBS- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- Synthetic Peptide within Human SLC6A12 aa 500-600. The exact immunogen used to generate this antibody is proprietary information. Database link P48065
Reactivity data
Select an application| WB | |
|---|---|
| Human | Tested |
| Mouse | Tested |
| Rat | Tested |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/500 | Notes - |
Species Mouse | Dilution info 1/500 | Notes - |
Species Rat | Dilution info 1/500 | Notes - |
Target data
Function
Transporter that mediates cellular uptake of betaine and GABA in a sodium- and chloride-dependent process (PubMed:7589472). May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation. Probably also involved in renal and hepatic osmotic regulation (By similarity).
Alternative names
BGT1, SLC6A12, Sodium- and chloride-dependent betaine transporter, BGT-1, Na(+)/Cl(-) betaine/GABA transporter, Solute carrier family 6 member 12
Recommended products
Rabbit Polyclonal BGT-1 antibody. Suitable for WB and reacts with Human, Mouse, Rat samples. Cited in 2 publications. Immunogen corresponding to Synthetic Peptide within Human SLC6A12 aa 500-600.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.2
Preservative: 0.097% Sodium azide
Constituents: 99% PBS- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- Synthetic Peptide within Human SLC6A12 aa 500-600. The exact immunogen used to generate this antibody is proprietary information. Database link P48065
- Purification technique
- Affinity purification Immunogen
- Concentration
- Purification notes
Purity is > 95% (by SDS-PAGE).
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
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1 product image
Western blot - Anti-BGT-1 antibody (ab200676)
All lanes: Western blot - Anti-BGT-1 antibody (ab200676)
Lane 1: HEK293T whole cell lysate
Lane 2: sp2/0 whole cell lysate
Lane 3: PC12 whole cell lysate
Predicted band size: 69 kDa
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