AB204791

Anti-BHLHB5 antibody

Name: Anti-BHLHB5 antibody (ab204791) | Abcam
Brand: Abcam Limited
SKU: AB204791
Rating: 5 (2 reviews)

(2 Reviews)

(4 Publications)

Rabbit Polyclonal BHLHB5 antibody. Suitable for IHC-P and reacts with Human samples. Cited in 4 publications. Immunogen corresponding to Recombinant Fragment Protein within Human BHLHE22 aa 1-100.

View Alternative Names

BHLHB5, TNRC20, BHLHE22, Class E basic helix-loop-helix protein 22, bHLHe22, Class B basic helix-loop-helix protein 5, Trinucleotide repeat-containing gene 20 protein, bHLHb5

1 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BHLHB5 antibody (AB204791)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BHLHB5 antibody (AB204791)

Immunohistochemical analysis of paraffin embedded Human cerebellum tissue labeling BHLHB5 with ab204791 at 1/2500 dilution.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human BHLHE22 aa 1-100. The exact immunogen used to generate this antibody is proprietary information.

Q8NFJ8

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/2500 - 1/5000", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol." }, "Mouse": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Hamster": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Storage buffer

pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Inhibits DNA binding of TCF3/E47 homodimers and TCF3 (E47)/NEUROD1 heterodimers and acts as a strong repressor of Neurod1 and Myod-responsive genes, probably by heterodimerization with class a basic helix-loop-helix factors. Despite the presence of an intact basic domain, does not bind to DNA (By similarity). In the brain, may function as an area-specific transcription factor that regulates the postmitotic acquisition of area identities and elucidate the genetic hierarchy between progenitors and postmitotic neurons driving neocortical arealization. May be required for the survival of a specific population of inhibitory neurons in the superficial laminae of the spinal cord dorsal horn that may regulate pruritis. Seems to play a crucial role in the retinogenesis, in the specification of amacrine and bipolar subtypes. Forms with PRDM8 a transcriptional repressor complex controlling genes involved in neural development and neuronal differentiation.

See full target information BHLHE22

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Publications (4)

Recent publications for all applications. Explore the full list and refine your search

Nature 638:469-478 PubMed39814878

2025

Specification of claustro-amygdalar and palaeocortical neurons and circuits.

Applications

Unspecified application

Species

Unspecified reactive species

Navjot Kaur,Rothem Kovner,Forrest O Gulden,Mihovil Pletikos,David Andrijevic,Tianjia Zhu,John Silbereis,Mikihito Shibata,Akemi Shibata,Yuting Liu,Shaojie Ma,Nikkita Salla,Xabier de Martin,Thomas S Klarić,Megan Burke,Daniel Franjic,Hyesun Cho,Matthew Yuen,Ipsita Chatterjee,Paula Soric,Devippriya Esakkimuthu,Markus Moser,Gabriel Santpere,Yann S Mineur,Kartik Pattabiraman,Marina R Picciotto,Hao Huang,Nenad Sestan

Neuroscience 455:65-78 PubMed33346116

2020

Atypical Neocortical Development in the Cited2 Conditional Knockout Leads to Behavioral Deficits Associated with Neurodevelopmental Disorders.

Applications

Unspecified application

Species

Unspecified reactive species

Nikolaus R Wagner,Jessica L MacDonald

Nature communications 11:4287 PubMed32855419

2020

Warsaw Breakage Syndrome associated DDX11 helicase resolves G-quadruplex structures to support sister chromatid cohesion.

Applications

Unspecified application

Species

Unspecified reactive species

Janne J M van Schie,Atiq Faramarz,Jesper A Balk,Grant S Stewart,Erika Cantelli,Anneke B Oostra,Martin A Rooimans,Joanna L Parish,Cynthia de Almeida Estéves,Katja Dumic,Ingeborg Barisic,Karin E M Diderich,Marjon A van Slegtenhorst,Mohammad Mahtab,Francesca M Pisani,Hein Te Riele,Najim Ameziane,Rob M F Wolthuis,Job de Lange

Frontiers in cell and developmental biology 7:351 PubMed31921861

2019

Role of TGF-β/Smad Pathway in the Transcription of Pancreas-Specific Genes During Beta Cell Differentiation.

Applications

Unspecified application

Species

Unspecified reactive species

Yuhua Gao,Ranxi Zhang,Shanshan Dai,Xue Zhang,Xiangchen Li,Chunyu Bai

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-BHLHB5 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BHLHB5 antibody (AB204791)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Complementary Products

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (4)

Product promise