AB28065

Biotin Anti-CD41 antibody [MEM-06]

Name: Biotin Anti-CD41 antibody [MEM-06] (ab28065) | Abcam
Brand: Abcam Limited
SKU: AB28065
Price: 525 USD
Availability: InStock

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(2 Publications)

Mouse Monoclonal CD41 antibody - conjugated to Biotin. Suitable for Flow Cyt and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Cell preparation containing ITGA2B protein.

View Alternative Names

CD41, GP2B, ITGAB, ITGA2B, Integrin alpha-IIb, GPalpha IIb, Platelet membrane glycoprotein IIb, GPIIb

1 Images

Flow Cytometry - Biotin Anti-CD41 antibody [MEM-06] (AB28065)

Flow Cyt

Supplier Data

Flow Cytometry - Biotin Anti-CD41 antibody [MEM-06] (AB28065)

Flow cytometry analysis (surface staining) of human platelets with ab28065.

Unconjugated

Anti-CD41 antibody [MEM-06]

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

MEM-06

Isotype

IgG1

Conjugation

Biotin

Excitation/Emission

Carrier free

Reacts with

Human

Applications

Flow Cyt

applications

Immunogen

Cell preparation containing ITGA2B protein. The exact immunogen used to generate this antibody is proprietary information.

P08514

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "2 µg/mL", "FlowCyt-species-notes": "<p><a href='/en-us/products/primary-antibodies/biotin-mouse-igg1-kappa-monoclonal-mopc-21-isotype-control-ab18434'>ab18434</a> - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.</p>" } } }

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Product details

The purified antibody is conjugated with Biotin-LC-NHS under optimum conditions. The reagent is free of unconjugated biotin.

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Properties and storage information

Form

Liquid

Storage buffer

pH: 7.4 Preservative: 0.097% Sodium azide Constituents: PBS

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Integrin alpha-IIb/beta-3 (ITGA2B : ITGB3) is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain (By similarity). Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen (PubMed : 9111081). This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface (By similarity). Integrin ITGA2B : ITGB3 is also the receptor of erythrocyte-specific ICAM4 ligand involved in heterotypic cell-cell adhesion between erythrocytes and activated platelets (PubMed : 12477717).

See full target information ITGA2B

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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Thrombosis and haemostasis 118:1969-1981 PubMed30300910

2018

Monocytes of Different Subsets in Complexes with Platelets in Patients with Myocardial Infarction.

Applications

Unspecified application

Species

Unspecified reactive species

Marina Loguinova,Natalia Pinegina,Valeria Kogan,Murad Vagida,Anush Arakelyan,Alexander Shpektor,Leonid Margolis,Elena Vasilieva

Proceedings of the National Academy of Sciences of the United States of America 101:7064-9 PubMed15103024

2004

HLA-G1-expressing antigen-presenting cells induce immunosuppressive CD4+ T cells.

Applications

Unspecified application

Species

Unspecified reactive species

Joël LeMaoult,Irène Krawice-Radanne,Jean Dausset,Edgardo D Carosella

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Biotin Anti-CD41 antibody [MEM-06]

Flow Cytometry - Biotin Anti-CD41 antibody [MEM-06] (AB28065)

Related conjugates and formulations (1)

Key facts

Host species

Clonality

Clone number

Isotype

Conjugation

Excitation/Emission

Carrier free

Reacts with

Applications

Immunogen

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Reactivity data

Product details

Properties and storage information

Form

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Storage information

Product protocols

Target data

Publications (2)

Product promise