AB95727

Biotin Anti-CD41 antibody [MWReg30]

Name: Biotin Anti-CD41 antibody [MWReg30] (ab95727) | Abcam
Brand: Abcam Limited
SKU: AB95727
Price: 535 USD
Availability: InStock
Rating: 4 (1 reviews)

(1 Review)

(2 Publications)

Rat Monoclonal CD41 antibody - conjugated to Biotin. Suitable for Flow Cyt and reacts with Mouse samples. Cited in 2 publications. Immunogen corresponding to Cell preparation containing Itga2b protein.

View Alternative Names

CD41, Integrin alpha-IIb, GPalpha IIb, Platelet membrane glycoprotein IIb, GPIIb, Itga2b

1 Images

Flow Cytometry - Biotin Anti-CD41 antibody [MWReg30] (AB95727)

Flow Cyt

Unknown

Flow Cytometry - Biotin Anti-CD41 antibody [MWReg30] (AB95727)

Mouse platelets stained with 0.06 μg of ab95727 followed by Streptavidin PE.

Unconjugated

Anti-CD41 antibody [MWReg30]
660 APC

APC Anti-CD41 antibody [MWReg30]
578 PE

PE Anti-CD41 antibody [MWReg30]
778 PE/Cy7®

PE/Cy7® Anti-CD41 antibody [MWReg30]

Key facts

Host species

Rat

Clonality

Monoclonal

Clone number

MWReg30

Isotype

IgG1

Light chain type

kappa

Conjugation

Biotin

Excitation/Emission

Carrier free

Reacts with

Mouse

Applications

Flow Cyt

applications

Immunogen

Cell preparation containing Itga2b protein. The exact immunogen used to generate this antibody is proprietary information.

Q9QUM0

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "0.125 µL for 10^5-10^8 Cells", "FlowCyt-species-notes": "<p>(based on a final test voulme of 100 μl)</p><p><a href='/en-us/products/primary-antibodies/biotin-rat-igg1-kappa-rtk2071-isotype-control-ab18403'>ab18403</a> - Rat monoclonal IgG1, is suitable for use as an isotype control with this antibody.</p>" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein G

Storage buffer

pH: 7.2 Preservative: 0.09% Sodium azide Constituents: PBS

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Integrin alpha-IIb/beta-3 (ITGA2B : ITGB3) is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain (By similarity). Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen (By similarity). This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface (By similarity). Integrin ITGA2B : ITGB3 is also the receptor of erythrocyte-specific ICAM4 ligand involved in heterotypic cell-cell adhesion between erythrocytes and activated platelets (By similarity).

See full target information Itga2b

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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Aging 15:630-649 PubMed36734880

2023

Immune-mediated platelet depletion augments Alzheimer's disease neuropathological hallmarks in APP-PS1 mice.

Applications

Unspecified application

Species

Unspecified reactive species

Diana M Bessa de Sousa,Ariane Benedetti,Barbara Altendorfer,Heike Mrowetz,Michael S Unger,Katharina Schallmoser,Ludwig Aigner,Kathrin Maria Kniewallner

Blood 94:684-93 PubMed10397735

1999

Acute systemic reaction and lung alterations induced by an antiplatelet integrin gpIIb/IIIa antibody in mice.

Applications

Unspecified application

Species

Unspecified reactive species

B Nieswandt,B Echtenacher,F P Wachs,J Schröder,J E Gessner,R E Schmidt,G E Grau,D N Männel

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Biotin Anti-CD41 antibody [MWReg30]

Flow Cytometry - Biotin Anti-CD41 antibody [MWReg30] (AB95727)

Related conjugates and formulations (4)

Key facts

Host species

Clonality

Clone number

Isotype

Light chain type

Conjugation

Excitation/Emission

Carrier free

Reacts with

Applications

Immunogen

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Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Storage information

Product protocols

Target data

Publications (2)

Product promise