AB30400

Biotin Anti-CD42b antibody [AK2]

Name: Anti-CD42b Biotin antibody [AK2] (ab30400) Mouse monoclonal IgG1 | Abcam
Brand: Abcam Limited
SKU: AB30400
Price: 270 USD
Availability: InStock

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(2 Publications)

Mouse Monoclonal CD42b antibody - conjugated to Biotin. Suitable for Flow Cyt and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Cell preparation containing GP1BA protein.

View Alternative Names

CD42b, Platelet glycoprotein Ib alpha chain, GP-Ib alpha, GPIb-alpha, GPIbA, Glycoprotein Ibalpha, Antigen CD42b-alpha, GP1BA

1 Images

Flow Cytometry - Biotin Anti-CD42b antibody [AK2] (AB30400)

Flow Cyt

Unknown

Flow Cytometry - Biotin Anti-CD42b antibody [AK2] (AB30400)

Flow cytometric analysis of CD42b expressing cells in human periferal blood platelets using ab30400.

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

AK2

Isotype

IgG1

Conjugation

Biotin

Excitation/Emission

Carrier free

Reacts with

Human

Applications

Flow Cyt

applications

Immunogen

Cell preparation containing GP1BA protein. The exact immunogen used to generate this antibody is proprietary information.

P07359

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p>Use neat or 10μl for 100μl of whole blood.</p><p><a href='/en-us/products/primary-antibodies/biotin-mouse-igg1-kappa-monoclonal-mopc-21-isotype-control-ab18434'>ab18434</a> - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.</p>" } } }

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Product details

Clone AK2 has been reported to block the binding of von Willebrand Factor to platelets.

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein G

Storage buffer

pH: 7.4 Preservative: 0.09% Sodium azide Constituents: PBS, 1% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

GP-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to the A1 domain of vWF, which is already bound to the subendothelium.

See full target information GP1BA

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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

British journal of haematology 166:571-80 PubMed24766273

2014

Small-size platelet microparticles trigger platelet and monocyte functionality and modulate thrombogenesis via P-selectin.

Applications

Unspecified application

Species

Unspecified reactive species

Silvia Montoro-García,Eduard Shantsila,Diana Hernández-Romero,Eva Jover,Mariano Valdés,Francisco Marín,Gregory Y H Lip

Biophysical journal 85:4099-109 PubMed14645097

2003

Kinetics of GPIbalpha-vWF-A1 tether bond under flow: effect of GPIbalpha mutations on the association and dissociation rates.

Applications

Unspecified application

Species

Unspecified reactive species

R Anand Kumar,Jing-fei Dong,Jenny A Thaggard,Miguel A Cruz,José A López,Larry V McIntire

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Biotin Anti-CD42b antibody [AK2]

Flow Cytometry - Biotin Anti-CD42b antibody [AK2] (AB30400)

Key facts

Host species

Clonality

Clone number

Isotype

Conjugation

Excitation/Emission

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Product details

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Storage information

Product protocols

Target data

Publications (2)

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Product promise