AB28105

Biotin Anti-CD44 antibody [MEM-85]

Name: Anti-CD44 Biotin antibody [MEM-85] (ab28105) Mouse monoclonal IgG2b | Abcam
Brand: Abcam Limited
SKU: AB28105
Price: 495 USD
Availability: InStock

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(1 Publication)

Mouse Monoclonal CD44 antibody - conjugated to Biotin. Suitable for Flow Cyt and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Cell preparation containing CD44 protein.

View Alternative Names

CD44, LHR, MDU2, MDU3, MIC4, CD44 antigen, CDw44, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, Phagocytic glycoprotein 1, Phagocytic glycoprotein I, ECMR-III, PGP-1, PGP-I

1 Images

Flow Cytometry - Biotin Anti-CD44 antibody [MEM-85] (AB28105)

Flow Cyt

Supplier Data

Flow Cytometry - Biotin Anti-CD44 antibody [MEM-85] (AB28105)

Analysis by flow cytometry of ab28105 staining CD44 in human peripheral blood leukocytes.

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

MEM-85

Isotype

IgG2b

Conjugation

Biotin

Excitation/Emission

Carrier free

Reacts with

Human

Applications

Flow Cyt

applications

Immunogen

Cell preparation containing CD44 protein. The exact immunogen used to generate this antibody is proprietary information.

P16070

Specificity

The antibody reacts with both cell surface-expressed and soluble form of CD44 antigen.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "1-3 µg/mL", "FlowCyt-species-notes": "<p><a href='/en-us/products/primary-antibodies/biotin-mouse-igg2b-kappa-monoclonal-mpc-11-isotype-control-ab18418'>ab18418</a> - Mouse monoclonal IgG2b, is suitable for use as an isotype control with this antibody.</p>" } } }

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Product details

The purified antibody is conjugated with Biotin-LC-NHS.

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein A

Storage buffer

pH: 7.4 Preservative: 0.097% Sodium azide Constituents: PBS

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

The protein expressed by gene CD44 functions as a cell-surface receptor involved in cell-cell interactions, cell adhesion, and migration, allowing cells to detect and react to changes in their tissue microenvironment. It is implicated in numerous cellular processes, including the activation, recirculation, and homing of T-lymphocytes, hematopoiesis, inflammation, and the response to bacterial infection. Through its ectodomain, CD44 interacts with extracellular matrix components like hyaluronan, collagen, growth factors, cytokines, and proteases, serving as a platform for signal transduction by forming protein complexes with receptor kinases and membrane proteases via its cytoplasmic domain. Effectors such as PKN2, the RhoGTPases RAC1 and RHOA, Rho-kinases, and phospholipase C coordinate signaling pathways that promote calcium mobilization and actin-mediated cytoskeleton reorganization crucial for cell migration and adhesion. This supplementary information is collated from multiple sources and compiled automatically.

See full target information CD44

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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

European journal of immunology 25:1051-5 PubMed7537669

1995

MEM-59 monoclonal antibody detects a CD43 epitope involved in lymphocyte activation.

Applications

Unspecified application

Species

Unspecified reactive species

M Alvarado,C Klassen,J Cerny,V Horejsí,R E Schmidt

View all publications

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