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AB183395

Biotin Anti-DNA/RNA Damage antibody [15A3]

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(1 Publication)

Mouse Monoclonal DNA/RNA Damage antibody - conjugated to Biotin. Suitable for ICC, IHC-P, IHC-Fr and reacts with Nucleic Acid samples. Cited in 1 publication. Immunogen corresponding to Chemical / Small Molecule corresponding to DNA/RNA Damage.

View Alternative Names

7,8-Dihydro-8-oxo-2'-deoxyguanosine, 7,8-Dihydro-8-oxodeoxyguanosine, 7,8-Dihydro-8-oxoguanine, 8-Hydroxy-2'-deoxyguanosine, 8-Hydroxydeoxyguanosine, 8-OH-dG, 8-Oxo-2'-deoxyguanosine, 8-Oxo-7,8-dihydro-2'-deoxyguanosine (Oxo-8-dG), 8-Oxo-7,8-dihydrodeoxyguanosine, 8-Oxo-G, 8-Oxo-dG, 8-Oxo-guanosine, 8-Oxo-riboguanosine, 8-Oxoguanine, 8-hydroxyguanine, 8-oxo-7,8-dihydroguanine (Oxo-8-Gua), 8-oxo-7,8-dihydroguanosine (Oxo-8-G), 8-oxo-Gua, OH8Gua

  • Unconjugated

    Anti-DNA/RNA Damage antibody [15A3]

  • 519 FITC

    FITC Anti-DNA/RNA Damage antibody [15A3]

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

15A3

Isotype

IgG2b

Conjugation

Biotin

Excitation/Emission
Carrier free

No

Applications

IHC-P, IHC-Fr, ICC

applications

Specificity

15A3 binds with high specificity and affinity to oxo8dG (8-hydroxy-2'-deoxyguanosine), oxo8Gua (8-oxo-7,8-dihydroguanine), and oxo8G (8-oxo-7,8-dihydroguanosine) present in biological fluids with Kaff values of 9.2 x 108 M-1, 4.7 x' 17 M-1, and 2.1 x 108 M-1, respectively.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICC" : {"fullname" : "Immunocytochemistry", "shortname":"ICC"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "IHCFr" : {"fullname" : "Immunohistochemistry (Frozen sections)", "shortname":"IHC-Fr"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Nucleic Acid": { "ICC-species-checked": "guaranteed", "ICC-species-dilution-info": "", "ICC-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein G
Storage buffer
Preservative: 0.09% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle|Store in the dark
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

See full target information DNA/RNA Damage
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Proceedings of the National Academy of Sciences of the United States of America 89:3375-9 PubMed1565629

1992

Assay of excised oxidative DNA lesions: isolation of 8-oxoguanine and its nucleoside derivatives from biological fluids with a monoclonal antibody column.

Applications

Unspecified application

Species

Unspecified reactive species

E M Park,M K Shigenaga,P Degan,T S Korn,J W Kitzler,C M Wehr,P Kolachana,B N Ames
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Alternative Products

Primary Antibodies

AB183393

FITC Anti-DNA/RNA Damage antibody [15A3]

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - FITC Anti-DNA/RNA Damage antibody [15A3] (AB183393)

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Complementary Products

Primary Antibodies

AB183393

FITC Anti-DNA/RNA Damage antibody [15A3]

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - FITC Anti-DNA/RNA Damage antibody [15A3] (AB183393)

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  • 1
Primary Antibodies

AB62623

Anti-DNA/RNA Damage antibody [15A3]

Immunocytochemistry - Anti-DNA/RNA Damage antibody [15A3] (AB62623)

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Reagents, Controls & Accessories

AB2601

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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