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Mouse Monoclonal Fc epsilon RI/FCER1A antibody - conjugated to Biotin. Suitable for WB, Flow Cyt, ICC/IF and reacts with Human samples. Cited in 5 publications. Immunogen corresponding to Recombinant Fragment Protein within Human FCER1A aa 50-200.

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Publications

Key facts

Isotype
IgG1
Host species
Mouse
Conjugation
Biotin
Storage buffer

pH: 6 - 8.5
Constituents: 50% Glycerol (glycerin, glycerine), 49% PBS

Form
Liquid
Clonality
Monoclonal

Immunogen

  • Recombinant Fragment Protein within Human FCER1A aa 50-200. The exact immunogen used to generate this antibody is proprietary information. Database link P12319

Reactivity data

Select an application
Product promiseTestedExpectedPredictedNot recommended
WBFlow CytICC/IF
Human
Expected
Expected
Expected

Expected
Expected

Species
Human
Dilution info
1 µg/mL
Notes

-

Expected
Expected

Species
Human
Dilution info
Use at an assay dependent concentration.
Notes

-

Expected
Expected

Species
Human
Dilution info
Use at an assay dependent concentration.
Notes

-

Associated Products

Select an associated product type

4 products for Alternative Product

Target data

Function

High-affinity receptor for immunoglobulin epsilon/IgE. Mediates IgE effector functions in myeloid cells. Upon IgE binding and antigen/allergen cross-linking initiates signaling pathways that lead to myeloid cell activation and differentiation. On mast cells, basophils and eosinophils stimulates the secretion of vasoactive amines, lipid mediators and cytokines that contribute to inflammatory response, tissue remodeling and cytotoxicity against microbes. Triggers the immediate hypersensitivity response to allergens as a host defense mechanism against helminth parasites, pathogenic bacteria and venom toxicity. When dysregulated, it can elicit harmful life-threatening allergic and anaphylactic reactions.

Alternative names

Recommended products

Mouse Monoclonal Fc epsilon RI/FCER1A antibody - conjugated to Biotin. Suitable for WB, Flow Cyt, ICC/IF and reacts with Human samples. Cited in 5 publications. Immunogen corresponding to Recombinant Fragment Protein within Human FCER1A aa 50-200.

Key facts

Isotype
IgG1
Conjugation
Biotin
Form
Liquid
Clonality
Monoclonal
Immunogen
  • Recombinant Fragment Protein within Human FCER1A aa 50-200. The exact immunogen used to generate this antibody is proprietary information. Database link P12319
Clone number
CRA2
Purification technique
Ion exchange chromatography
Light chain type
kappa
Concentration
Loading...
Purification notes

The IgG fraction was purified from serum free culture medium of mouse hybridoma by propriety chromatography under mild conditions.Filter sterilized.

Storage

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Storage information
Avoid freeze / thaw cycle

Notes

[biotin]/[IgG] = 6.9

Product promise

We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.

In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
Terms & Conditions.

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