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AB122915

Biotin Anti-Fc epsilon RI/FCER1A antibody [CRA2]

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(5 Publications)

Mouse Monoclonal Fc epsilon RI/FCER1A antibody - conjugated to Biotin. Suitable for WB, Flow Cyt, ICC/IF and reacts with Human samples. Cited in 5 publications. Immunogen corresponding to Recombinant Fragment Protein within Human FCER1A aa 50-200.

View Alternative Names

FCE1A, FCER1A, High affinity immunoglobulin epsilon receptor subunit alpha, Fc-epsilon RI-alpha, IgE Fc receptor subunit alpha, FcERI

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

CRA2

Isotype

IgG1

Light chain type

kappa

Conjugation

Biotin

Excitation/Emission
Carrier free

No

Reacts with

Human

Applications

Flow Cyt, ICC/IF, WB

applications

Immunogen

Recombinant Fragment Protein within Human FCER1A aa 50-200. The exact immunogen used to generate this antibody is proprietary information.

P12319

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Alternative Products

Primary Antibodies

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Primary Antibodies

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APC Anti-Fc epsilon RI/FCER1A antibody [AER-37 (CRA1)]

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Primary Antibodies

AB171278

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Primary Antibodies

AB122882

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Complementary Products

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Primary Antibodies

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Primary Antibodies

AB45143

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Primary Antibodies

AB40766

Anti-c-Jun antibody [EP693Y]

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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-c-Jun antibody [EP693Y] (AB40766)

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Primary Antibodies

AB10558

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  • 61
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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "1 µg/mL", "WB-species-notes": "<p></p>", "FlowCyt-species-checked": "guaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>" } } }
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Product details

[biotin]/[IgG] = 6.9
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Properties and storage information

Form
Liquid
Purification technique
Ion exchange chromatography
Purification notes
The IgG fraction was purified from serum free culture medium of mouse hybridoma by propriety chromatography under mild conditions.Filter sterilized.
Storage buffer
pH: 6 - 8.5 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

High-affinity receptor for immunoglobulin epsilon/IgE. Mediates IgE effector functions in myeloid cells. Upon IgE binding and antigen/allergen cross-linking initiates signaling pathways that lead to myeloid cell activation and differentiation. On mast cells, basophils and eosinophils stimulates the secretion of vasoactive amines, lipid mediators and cytokines that contribute to inflammatory response, tissue remodeling and cytotoxicity against microbes. Triggers the immediate hypersensitivity response to allergens as a host defense mechanism against helminth parasites, pathogenic bacteria and venom toxicity. When dysregulated, it can elicit harmful life-threatening allergic and anaphylactic reactions.
See full target information FCER1A
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Publications (5)

Recent publications for all applications. Explore the full list and refine your search

Journal of dermatological science 27:156-61 PubMed11641054

2001

Enhanced expression of the high-affinity receptor for IgE (Fc(epsilon)RI) associated with decreased numbers of Langerhans cells in the lesional epidermis of atopic dermatitis.

Applications

Unspecified application

Species

Unspecified reactive species

T Goto,Y Soma,C Ra,Y Kawa,Y Kubota,M Mizoguchi

Bioscience, biotechnology, and biochemistry 65:79-85 PubMed11272849

2001

Direct expression of the extracellular portion of human FcepsilonRIalpha chain as inclusion bodies in Escherichia coli.

Applications

Unspecified application

Species

Unspecified reactive species

T Takai,K Okumura,C Ra

Bioscience, biotechnology, and biochemistry 64:1856-67 PubMed11055388

2000

Epitope analysis and primary structures of variable regions of anti-human FcepsilonRI monoclonal antibodies, and expression of the chimeric antibodies fused with human constant regions.

Applications

Unspecified application

Species

Unspecified reactive species

T Takai,T Yuuki,N Iwamoto-Yasue,K Okumura,C Ra

Blood 93:2543-51 PubMed10194433

1999

Functional expression of the high affinity receptor for IgE (FcepsilonRI) in human platelets and its' intracellular expression in human megakaryocytes.

Applications

Unspecified application

Species

Unspecified reactive species

S Hasegawa,R Pawankar,K Suzuki,T Nakahata,S Furukawa,K Okumura,C Ra

The Journal of biological chemistry 265:22079-81 PubMed2148316

1990

The alpha subunit of the human IgE receptor (FcERI) is sufficient for high affinity IgE binding.

Applications

Unspecified application

Species

Unspecified reactive species

J Hakimi,C Seals,J A Kondas,L Pettine,W Danho,J Kochan
View all publications
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Product promise

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