AB51416

Biotin Anti-Fibrinogen antibody

Name: Biotin Anti-Fibrinogen antibody (ab51416) | Abcam
Brand: Abcam Limited
SKU: AB51416
Price: 525 USD
Availability: InStock

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(6 Publications)

Rabbit Polyclonal Fibrinogen alpha chain antibody - conjugated to Biotin. Suitable for IP, ELISA, WB, RIA, EIA and reacts with Rat samples. Cited in 6 publications. Immunogen corresponding to Native Full Length Protein corresponding to Rat Fga.

View Alternative Names

Fibrinogen alpha chain, Fga

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Conjugation

Biotin

Excitation/Emission

Carrier free

Reacts with

Rat

Applications

ELISA, WB, IP, RIA, EIA

applications

Immunogen

Native Full Length Protein corresponding to Rat Fga.

P06399

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "RIA" : {"fullname" : "Radioimmunoassay", "shortname":"RIA"}, "EIA" : {"fullname" : "Enzyme Immunoassay", "shortname":"EIA"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Rat": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "A band of 340 kDa is seen when run in native gel.", "RIA-species-checked": "guaranteed", "RIA-species-dilution-info": "", "RIA-species-notes": "", "EIA-species-checked": "guaranteed", "EIA-species-dilution-info": "", "EIA-species-notes": "" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein G

Storage buffer

pH: 7.5 Preservative: 0.01% Thimerosal (merthiolate) Constituents: PBS, 50% Glycerol (glycerin, glycerine)

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the immune response via both innate and T-cell mediated pathways.

See full target information Fga

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Publications (6)

Recent publications for all applications. Explore the full list and refine your search

Nature communications 15:3784 PubMed38710716

2024

Targeted delivery of the probiotic Saccharomyces boulardii to the extracellular matrix enhances gut residence time and recovery in murine colitis.

Applications

Unspecified application

Species

Unspecified reactive species

Mairead K Heavey,Anthony Hazelton,Yuyan Wang,Mitzy Garner,Aaron C Anselmo,Janelle C Arthur,Juliane Nguyen

Neuroscience bulletin 40:35-49 PubMed37608137

2023

Impairment of Autophagic Flux After Hypobaric Hypoxia Potentiates Oxidative Stress and Cognitive Function Disturbances in Mice.

Applications

Unspecified application

Species

Unspecified reactive species

Shuhui Dai,Yuan Feng,Chuanhao Lu,Hongchen Zhang,Wenke Ma,Wenyu Xie,Xiuquan Wu,Peng Luo,Lei Zhang,Fei Fei,Zhou Fei,Xia Li

Autophagy 17:1142-1156 PubMed32249716

2020

The AMPK-MFN2 axis regulates MAM dynamics and autophagy induced by energy stresses.

Applications

Unspecified application

Species

Unspecified reactive species

Yongquan Hu,Hao Chen,Luying Zhang,Xiaoying Lin,Xia Li,Haixia Zhuang,Hualin Fan,Tian Meng,Zhengjie He,Haofeng Huang,Qing Gong,Dongxing Zhu,Yiming Xu,Pengcheng He,Longxuan Li,Du Feng

Experimental cell research 387:111772 PubMed31836471

2019

Sodium butyrate causes α-synuclein degradation by an Atg5-dependent and PI3K/Akt/mTOR-related autophagy pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Chen-Meng Qiao,Meng-Fei Sun,Xue-Bing Jia,Yun Shi,Bo-Ping Zhang,Zhi-Lan Zhou,Li-Ping Zhao,Chun Cui,Yan-Qin Shen

Frontiers in immunology 8:1507 PubMed29250056

2017

Reduced Endoplasmic Reticulum Stress-Mediated Autophagy Is Required for Leptin Alleviating Inflammation in Adipose Tissue.

Applications

Unspecified application

Species

Unspecified reactive species

Lu Gan,Zhenjiang Liu,Dan Luo,Qian Ren,Hua Wu,Changxing Li,Chao Sun

Neuroscience letters 634:7-12 PubMed27693566

2016

The effects of poloxamer 188 on the autophagy induced by traumatic brain injury.

Applications

Unspecified application

Species

Unspecified reactive species

Haijun Bao,Xiaofang Yang,Ying Zhuang,Yuxiu Huang,Tao Wang,Mingyang Zhang,Dingkun Dai,Shaoxian Wang,Hua Xiao,Gengping Huang,Jinxia Kuai,Luyang Tao

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Biotin Anti-Fibrinogen antibody

Key facts

Host species

Clonality

Isotype

Conjugation

Excitation/Emission

Carrier free

Reacts with

Applications

Immunogen

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Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Storage information

Product protocols

Target data

Publications (6)

Product promise