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Rabbit Polyclonal Fibrinogen alpha chain antibody - conjugated to Biotin. Suitable for IP, ELISA, WB, RIA, EIA and reacts with Rat samples. Cited in 5 publications.

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Publications

Key facts

Isotype
IgG
Host species
Rabbit
Conjugation
Biotin
Storage buffer

pH: 7.5
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: PBS, 50% Glycerol (glycerin, glycerine)

Form
Liquid
Clonality
Polyclonal

Immunogen

Reactivity data

Select an application
Product promiseTestedExpectedPredictedNot recommended
IPELISAWBRIAEIA
Rat
Expected
Expected
Expected
Expected
Expected

Expected
Expected

Species
Rat
Dilution info
Use at an assay dependent concentration.
Notes

-

Expected
Expected

Species
Rat
Dilution info
Use at an assay dependent concentration.
Notes

-

Expected
Expected

Species
Rat
Dilution info
-
Notes

A band of 340 kDa is seen when run in native gel.

Expected
Expected

Species
Rat
Dilution info
Use at an assay dependent concentration.
Notes

-

Expected
Expected

Species
Rat
Dilution info
Use at an assay dependent concentration.
Notes

-

Associated Products

Select an associated product type

7 products for Alternative Product

Target data

Function

Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the immune response via both innate and T-cell mediated pathways.

Alternative names

Recommended products

Rabbit Polyclonal Fibrinogen alpha chain antibody - conjugated to Biotin. Suitable for IP, ELISA, WB, RIA, EIA and reacts with Rat samples. Cited in 5 publications.

Key facts

Isotype
IgG
Conjugation
Biotin
Form
Liquid
Clonality
Polyclonal
Immunogen
Purification technique
Affinity purification Protein G
Concentration
Loading...

Storage

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Storage information
Avoid freeze / thaw cycle

Notes

Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.

If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.

Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.

Product promise

We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.

In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
Terms & Conditions.

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    Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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