Biotin Anti-Galectin 3 antibody [M3/38]
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(1 Publication)
Rat Monoclonal Galectin 3 antibody - conjugated to Biotin. Suitable for Flow Cyt and reacts with Mouse, Human samples. Cited in 1 publication. Immunogen corresponding to Native Full Length Protein corresponding to Mouse Lgals3.
View Alternative Names
Galectin-3, Gal-3, 35 kDa lectin, Carbohydrate-binding protein 35, Galactose-specific lectin 3, IgE-binding protein, L-34 galactoside-binding lectin, Laminin-binding protein, Lectin L-29, Mac-2 antigen, CBP 35, Lgals3
- Flow Cyt
Unknown
Flow Cytometry - Biotin Anti-Galectin 3 antibody [M3/38] (AB95679)
ab95679 at 0.125μg dilution staining the monocyte population in normal human peripheral blood cells by Flow Cytometry followed by Streptavidin PE.
- Flow Cyt
Unknown
Flow Cytometry - Biotin Anti-Galectin 3 antibody [M3/38] (AB95679)
ab95679 at 0.125μg dilution staining Galectin 3 in C57BL/6 mouse bone marrow cells by Flow Cytometry (shown in blue) followed by Streptavidin PE.
Reactivity data
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Supplementary information
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Biological function summary
Galectin-3 participates in cell growth regulation apoptosis and immune system modulation. Galectin-3 does not typically integrate into larger molecular complexes but it interacts with a variety of cell surface and extracellular matrix molecules. Its function influences processes like cell differentiation and angiogenesis where it can act as a regulator leveraging its ability to bind glycans on cell surfaces and matrix components.
Pathways
Galectin-3 contributes to the regulation of pathways such as the MAPK signaling pathway and the Wnt signaling pathway. In the MAPK pathway it influences cell proliferation and survival. Galectin-3 interacts with proteins like β-catenin in the Wnt pathway assisting in transcriptional regulation and cell fate determination. These pathways are vital for maintaining cellular homeostasis and responding to extracellular signals.
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Target data
Publications (1)
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Journal of immunological methods 169:153-61 PubMed7510757
1994
Applications
Unspecified application
Species
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