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AB20055

Biotin Anti-Influenza B Virus antibody

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(1 Publication)

Goat Polyclonal Influenza B Virus antibody - conjugated to Biotin. Suitable for ICC/IF and reacts with Influenza B samples. Cited in 1 publication. Immunogen corresponding to Virus preparation containing Influenza B Virus protein.

Key facts

Host species

Goat

Clonality

Polyclonal

Isotype

IgG

Conjugation

Biotin

Excitation/Emission
Carrier free

No

Reacts with

Influenza B

Applications

ICC/IF

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Alternative Products

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Proteins & Peptides

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Influenza B": { "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p>Avidin and streptavidin amplification systems for fluorescence microscopy.</p>" } } }
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Product details

Covalently coupled with the N-Hydroxysuccinimide ester of biotin under mild conditions to give a high degree of substitution.
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Properties and storage information

Form
Liquid
Purity
IgG fraction
Storage buffer
Preservative: 0.1% Sodium azide Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Influenza B virus also known as flu B is an important pathogen in humans. It is part of the Orthomyxoviridae family and consists of a segmented RNA genome. The virus includes various structural proteins such as hemagglutinin (HA) and neuraminidase (NA) which are main surface proteins and matrix proteins. HA has a mass around 75 kDa and is key in virus attachment to host cells. This virus expresses itself mainly in the respiratory tract where it causes infections.
Biological function summary

Influenza B virus plays a significant role in viral infection by mediating cell entry. It is part of a complex life cycle involving binding to sialic acid receptors on host cells through HA causing uptake of the virus. The RNA genome replication and protein synthesis occur in the host cell's nucleus. The release of new virus particles happens through budding facilitated by NA. This virus contributes to the spread of infection among humans impacting healthcare systems.

Pathways

The lifecycle of the Influenza B virus integrates with cellular mechanisms of the host. The replication involves host pathways for RNA transcription and translation. It is related to the activation of immune response pathways including interferon signaling. The virus interacts with cellular proteins such as MxA which is part of the antiviral defense mechanism aimed to hinder viral replication.

Influenza B virus links to seasonal flu epidemics causing respiratory illnesses in populations. It often leads to complications such as bronchitis or pneumonia especially in vulnerable groups. The virus also contributes to exacerbation of chronic conditions like asthma. Hemagglutinin and neuraminidase key proteins of the virus often change through antigenic drift allowing the virus to evade immune detection and complicating vaccine development and effectiveness.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

See full target information Influenza B Virus
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Allergy 74:1956-1968 PubMed31102539

2019

Only α-Gal bound to lipids, but not to proteins, is transported across enterocytes as an IgE-reactive molecule that can induce effector cell activation.

Applications

Unspecified application

Species

Unspecified reactive species

Patricia Román-Carrasco,Barbara Lieder,Veronika Somoza,Marta Ponce,Zsolt Szépfalusi,Diana Martin,Wolfgang Hemmer,Ines Swoboda
View all publications
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Product promise

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