Goat Polyclonal Influenza B Virus antibody - conjugated to Biotin. Suitable for ICC/IF and reacts with Influenza B samples. Immunogen corresponding to Virus preparation containing Influenza B Virus protein.
Preservative: 0.1% Sodium azide
Constituents: 0.0268% PBS
ICC/IF | |
---|---|
Influenza B | Expected |
Species | Dilution info | Notes |
---|---|---|
Species Influenza B | Dilution info - | Notes Avidin and streptavidin amplification systems for fluorescence microscopy. |
Select an associated product type
Influenza B Virus NP, NP, Nucleocapsid protein, Nucleoprotein, Protein N
Goat Polyclonal Influenza B Virus antibody - conjugated to Biotin. Suitable for ICC/IF and reacts with Influenza B samples. Immunogen corresponding to Virus preparation containing Influenza B Virus protein.
Preservative: 0.1% Sodium azide
Constituents: 0.0268% PBS
Covalently coupled with the N-Hydroxysuccinimide ester of biotin under mild conditions to give a high degree of substitution.
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Influenza B virus also known as flu B is an important pathogen in humans. It is part of the Orthomyxoviridae family and consists of a segmented RNA genome. The virus includes various structural proteins such as hemagglutinin (HA) and neuraminidase (NA) which are main surface proteins and matrix proteins. HA has a mass around 75 kDa and is key in virus attachment to host cells. This virus expresses itself mainly in the respiratory tract where it causes infections.
Influenza B virus plays a significant role in viral infection by mediating cell entry. It is part of a complex life cycle involving binding to sialic acid receptors on host cells through HA causing uptake of the virus. The RNA genome replication and protein synthesis occur in the host cell's nucleus. The release of new virus particles happens through budding facilitated by NA. This virus contributes to the spread of infection among humans impacting healthcare systems.
The lifecycle of the Influenza B virus integrates with cellular mechanisms of the host. The replication involves host pathways for RNA transcription and translation. It is related to the activation of immune response pathways including interferon signaling. The virus interacts with cellular proteins such as MxA which is part of the antiviral defense mechanism aimed to hinder viral replication.
Influenza B virus links to seasonal flu epidemics causing respiratory illnesses in populations. It often leads to complications such as bronchitis or pneumonia especially in vulnerable groups. The virus also contributes to exacerbation of chronic conditions like asthma. Hemagglutinin and neuraminidase key proteins of the virus often change through antigenic drift allowing the virus to evade immune detection and complicating vaccine development and effectiveness.
We have tested this species and application combination and it works. It is covered by our product promise.
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
We do not recommend this combination. It is not covered by our product promise.
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