Biotin Mouse IgG1, Kappa Monoclonal [MOPC-21] - isotype control
IgG1
Mouse
Biotin
pH: 7.2
Preservative: 0.09% Sodium azide
Constituents: PBS
Liquid
Monoclonal
Application | Reactivity | Dilution info | Notes |
---|---|---|---|
Application Flow Cyt | Reactivity Expected | Dilution info - | Notes Surface or intracellular staining. |
Select an associated product type
Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
Immunoglobulin heavy constant gamma 4, Ig gamma-4 chain C region, IGHG4
Biotin Mouse IgG1, Kappa Monoclonal [MOPC-21] - isotype control
Immunoglobulin heavy constant gamma 4, Ig gamma-4 chain C region, IGHG4
IgG1
Mouse
Biotin
pH: 7.2
Preservative: 0.09% Sodium azide
Constituents: PBS
Liquid
Monoclonal
MOPC-21
Affinity purification
This clone has unknown specificity and was chosen as an isotype control after screening on a variety of resting, activated, live, and fixed rat and human tissues.
kappa
The immunoglobulin was purified by affinity chromatography, and conjugated with biotin under optimal conditions.
Blue Ice
+4°C
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