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AB48369

Biotin Anti-PPAR alpha antibody

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(2 Publications)

Rabbit Polyclonal PPAR alpha antibody - conjugated to Biotin. Suitable for IP, WB and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human PPARA.

View Alternative Names

NR1C1, PPAR, PPARA, Peroxisome proliferator-activated receptor alpha, PPAR-alpha, Nuclear receptor subfamily 1 group C member 1

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Conjugation

Biotin

Excitation/Emission
Carrier free

No

Reacts with

Human

Applications

WB, IP

applications

Immunogen

Recombinant Full Length Protein corresponding to Human PPARA.

Q07869

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Alternative Products

Primary Antibodies

AB3484

Anti-PPAR alpha (phospho S12) antibody

Western blot - Anti-PPAR alpha (phospho S12) antibody (AB3484)

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Primary Antibodies

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Primary Antibodies

AB245119

Anti-PPAR alpha antibody [EPR21244]

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beta Hydroxybutyrate (beta HB) Assay Kit (Colorimetric)

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Primary Antibodies

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Proteins & Peptides

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Cell Lines & Lysates

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "<p></p>", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein G
Storage buffer
pH: 7.5 Preservative: 0.01% Thimerosal (merthiolate) Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16 : 0/18 : 1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as a transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.
See full target information PPARA
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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Cancer cell 32:377-391.e9 PubMed28898698

2017

Enhancing CD8 T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy.

Applications

Unspecified application

Species

Unspecified reactive species

Ying Zhang,Raj Kurupati,Ling Liu,Xiang Yang Zhou,Gao Zhang,Abeer Hudaihed,Flavia Filisio,Wynetta Giles-Davis,Xiaowei Xu,Giorgos C Karakousis,Lynn M Schuchter,Wei Xu,Ravi Amaravadi,Min Xiao,Norah Sadek,Clemens Krepler,Meenhard Herlyn,Gordon J Freeman,Joshua D Rabinowitz,Hildegund C J Ertl

Investigative ophthalmology & visual science 28:604-7 PubMed3549614

1987

Immunoaffinity purification of S-antigen using monoclonal antibodies to different antigenic sites.

Applications

Unspecified application

Species

Unspecified reactive species

J P Banga,S Suleyman,E Kasp,E Brown,F LeRoy,M Sanders,D Dumonde
View all publications
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

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