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AB233505

Biotin Anti-VEGFB antibody

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(1 Publication)

Rabbit Polyclonal VEGFB antibody - conjugated to Biotin. Carrier free. Suitable for WB, sELISA and reacts with Recombinant full length protein - Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human VEGFB.

View Alternative Names

VRF, VEGFB, Vascular endothelial growth factor B, VEGF-B, VEGF-related factor

3 Images
Sandwich ELISA - Biotin Anti-VEGFB antibody (AB233505)
  • sELISA

Supplier Data

Sandwich ELISA - Biotin Anti-VEGFB antibody (AB233505)

ab233505, in conjunction with Anti-human VEGFB as a capture antibody, allows the detection of at least 2000-4000 pg/ml of Recombinant human VEGFB.

Western blot - Biotin Anti-VEGFB antibody (AB233505)
  • WB

Supplier Data

Western blot - Biotin Anti-VEGFB antibody (AB233505)

Non-reduced.

All lanes:

Western blot - Biotin Anti-VEGFB antibody (ab233505) at 0.2 µg/mL

Lane 1:

Recombinant human VEGFB protein, 250 ng

Lane 2:

Recombinant human VEGFB protein, 125 ng

Lane 3:

Recombinant human VEGFB protein, 62.5 ng

Lane 4:

Recombinant human VEGFB protein, 31.25 ng

Lane 5:

Recombinant human VEGFB protein, 15.625 ng

Lane 6:

Recombinant human VEGFB protein, 7.8 ng

Lane 7:

Recombinant human VEGFB protein, 3.9 ng

Lane 8:

Recombinant human VEGFB protein, 1.95 ng

Lane 9:

Recombinant human VEGFB protein, 0.98 ng

Lane 10:

Recombinant human VEGFB protein, 0.49 ng

Lane 11:

Recombinant human VEGFB protein, 0.24 ng

Predicted band size: 22 kDa

false

Western blot - Biotin Anti-VEGFB antibody (AB233505)
  • WB

Supplier Data

Western blot - Biotin Anti-VEGFB antibody (AB233505)

Reduced.

Lanes 1 - 10:

Western blot - Biotin Anti-VEGFB antibody (ab233505) at 0.2 µg/mL

Lane 11:

Western blot - Biotin Anti-VEGFB antibody (ab233505) at 0.2 µg

Lane 1:

Recombinant human VEGFB protein, 250 ng

Lane 2:

Recombinant human VEGFB protein, 125 ng

Lane 3:

Recombinant human VEGFB protein, 62.5 ng

Lane 4:

Recombinant human VEGFB protein, 31.25 ng

Lane 5:

Recombinant human VEGFB protein, 15.625 ng

Lane 6:

Recombinant human VEGFB protein, 7.8 ng

Lane 7:

Recombinant human VEGFB protein, 3.9 ng

Lane 8:

Recombinant human VEGFB protein, 1.95 ng

Lane 9:

Recombinant human VEGFB protein, 0.98 ng

Lane 10:

Recombinant human VEGFB protein, 0.49 ng

Lane 11:

Recombinant human VEGFB protein, 0.24 ng

Predicted band size: 22 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Conjugation

Biotin

Excitation/Emission
Carrier free

Yes

Reacts with

Human

Applications

sELISA, WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Human VEGFB.

P49765

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "sELISA" : {"fullname" : "Sandwich ELISA", "shortname":"sELISA"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "sELISA-species-checked": "predicted", "sELISA-species-dilution-info": "", "sELISA-species-notes": "" }, "Recombinant full length protein - Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.1-0.2 µg/mL", "WB-species-notes": "<p></p>", "sELISA-species-checked": "testedAndGuaranteed", "sELISA-species-dilution-info": "0.25-1 µg/mL", "sELISA-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Lyophilized
Purification technique
Affinity purification Immunogen
Purification notes
ab233505 purified by affinity chromatography and then biotinylated.
Storage buffer
Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle|Store in the dark
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

VEGFB also known as vascular endothelial growth factor B is a member of the VEGF family. It has a molecular mass of approximately 34-35 kDa. VEGFB interacts with its receptors to promote angiogenesis increasing blood supply to tissues. Expression of VEGFB occurs in the heart skeletal muscle and various endothelial cells. It also shows expression in tissues undergoing high metabolic activities. Besides its angiogenic role VEGFB exhibits participation in metabolic regulation.
Biological function summary

VEGFB supports angiogenesis by promoting endothelial cell growth and migration. It acts as a signal protein not forming part of a larger complex. VEGFB binds to VEGFR-1 (Flt-1) receptor which is involved in transmitting the growth-promoting signals. Its function extends to the regulation of fatty acid uptake into tissues highlighting its role in lipid metabolism and energy utilization.

Pathways

The signalling activities of VEGFB are significant in angiogenesis and metabolic pathways. VEGFB interacts closely with the VEGF-A pathway which is vital for forming new blood vessels. It also shares interactive roles with similar proteins such as VEGF-C and VEGF-D contributing to various angiogenic processes and cellular growth signalling systems.

Understanding VEGFB's role is important in conditions like cardiovascular disease and metabolic syndrome. Altered VEGFB signalling may link to heart diseases due to its regulatory function in maintaining heart vasculature. VEGFB has connections with VEGFR-1 and VEGF-A indicating its potential involvement in endothelial dysfunction and highlighting its significance in therapeutic strategies targeting such diseases.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis.
See full target information VEGFB
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

BMC cancer 25:1417 PubMed40898094

2025

KRAS mutation promotes immune escape of lung adenocarcinoma via ZNF24/SLC7A5/PD-L1 axis.

Applications

Unspecified application

Species

Unspecified reactive species

Leilei Li,Qiang Feng,Ya Jiang,Lilin Yang,Hong Fang,Wenmang Xu,Yuanyuan Wang,Xinyan Pan,Julun Yang
View all publications
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Product promise

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