Rabbit Polyclonal VEGFB antibody - conjugated to Biotin. Carrier free. Suitable for WB, sELISA and reacts with Recombinant full length protein - Human samples. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human VEGFB.
IgG
Rabbit
Biotin
Constituents: PBS
Lyophilized
Polyclonal
WB | sELISA | |
---|---|---|
Human | Predicted | Predicted |
Recombinant full length protein - Human | Tested | Tested |
Species | Dilution info | Notes |
---|---|---|
Species Recombinant full length protein - Human | Dilution info 0.10000-0.20000 µg/mL | Notes - |
Species | Dilution info | Notes |
---|---|---|
Species Human | Dilution info - | Notes - |
Species | Dilution info | Notes |
---|---|---|
Species Recombinant full length protein - Human | Dilution info 0.25000-1.00000 µg/mL | Notes - |
Species | Dilution info | Notes |
---|---|---|
Species Human | Dilution info - | Notes - |
Select an associated product type
Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis.
VRF, VRF, VEGFB, Vascular endothelial growth factor B, VEGF-B, VEGF-related factor, VRF
Rabbit Polyclonal VEGFB antibody - conjugated to Biotin. Carrier free. Suitable for WB, sELISA and reacts with Recombinant full length protein - Human samples. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human VEGFB.
IgG
Rabbit
Biotin
Constituents: PBS
Lyophilized
Polyclonal
Yes
Affinity purification Immunogen
ab233505 purified by affinity chromatography and then biotinylated.
Blue Ice
1-2 weeks
+4°C
-20°C
Upon delivery aliquot
Avoid freeze / thaw cycle, Store in the dark
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This supplementary information is collated from multiple sources and compiled automatically.
VEGFB also known as vascular endothelial growth factor B is a member of the VEGF family. It has a molecular mass of approximately 34-35 kDa. VEGFB interacts with its receptors to promote angiogenesis increasing blood supply to tissues. Expression of VEGFB occurs in the heart skeletal muscle and various endothelial cells. It also shows expression in tissues undergoing high metabolic activities. Besides its angiogenic role VEGFB exhibits participation in metabolic regulation.
VEGFB supports angiogenesis by promoting endothelial cell growth and migration. It acts as a signal protein not forming part of a larger complex. VEGFB binds to VEGFR-1 (Flt-1) receptor which is involved in transmitting the growth-promoting signals. Its function extends to the regulation of fatty acid uptake into tissues highlighting its role in lipid metabolism and energy utilization.
The signalling activities of VEGFB are significant in angiogenesis and metabolic pathways. VEGFB interacts closely with the VEGF-A pathway which is vital for forming new blood vessels. It also shares interactive roles with similar proteins such as VEGF-C and VEGF-D contributing to various angiogenic processes and cellular growth signalling systems.
Understanding VEGFB's role is important in conditions like cardiovascular disease and metabolic syndrome. Altered VEGFB signalling may link to heart diseases due to its regulatory function in maintaining heart vasculature. VEGFB has connections with VEGFR-1 and VEGF-A indicating its potential involvement in endothelial dysfunction and highlighting its significance in therapeutic strategies targeting such diseases.
We have tested this species and application combination and it works. It is covered by our product promise.
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
We do not recommend this combination. It is not covered by our product promise.
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Full details and terms and conditions can be found here:
Terms & Conditions.
Reduced.
Lanes 1, 10, 2, 3, 4, 5, 6, 7, 8 and 9: Western blot - Biotin Anti-VEGFB antibody (ab233505) at 0.2 µg/mL
Lane 11: Western blot - Biotin Anti-VEGFB antibody (ab233505) at 0.2 µg
Lane 1: Recombinant human VEGFB protein, 250 ng
Lane 2: Recombinant human VEGFB protein, 125 ng
Lane 3: Recombinant human VEGFB protein, 62.5 ng
Lane 4: Recombinant human VEGFB protein, 31.25 ng
Lane 5: Recombinant human VEGFB protein, 15.625 ng
Lane 6: Recombinant human VEGFB protein, 7.8 ng
Lane 7: Recombinant human VEGFB protein, 3.9 ng
Lane 8: Recombinant human VEGFB protein, 1.95 ng
Lane 9: Recombinant human VEGFB protein, 0.98 ng
Lane 10: Recombinant human VEGFB protein, 0.49 ng
Lane 11: Recombinant human VEGFB protein, 0.24 ng
Predicted band size: 22 kDa
Non-reduced.
All lanes: Western blot - Biotin Anti-VEGFB antibody (ab233505) at 0.2 µg/mL
Lane 1: Recombinant human VEGFB protein, 250 ng
Lane 2: Recombinant human VEGFB protein, 125 ng
Lane 3: Recombinant human VEGFB protein, 62.5 ng
Lane 4: Recombinant human VEGFB protein, 31.25 ng
Lane 5: Recombinant human VEGFB protein, 15.625 ng
Lane 6: Recombinant human VEGFB protein, 7.8 ng
Lane 7: Recombinant human VEGFB protein, 3.9 ng
Lane 8: Recombinant human VEGFB protein, 1.95 ng
Lane 9: Recombinant human VEGFB protein, 0.98 ng
Lane 10: Recombinant human VEGFB protein, 0.49 ng
Lane 11: Recombinant human VEGFB protein, 0.24 ng
Predicted band size: 22 kDa
ab233505, in conjunction with Anti-human VEGFB as a capture antibody, allows the detection of at least 2000-4000 pg/ml of Recombinant human VEGFB.
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