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AB278566

Anti-BLNK (phospho Y84) antibody [BLNKY84-H4]

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Rabbit Recombinant Monoclonal BLNK phospho Y84 antibody. Suitable for Flow Cyt and reacts with Human samples. Immunogen corresponding to Synthetic Peptide within Human BLNK phospho Y84.

View Alternative Names

BASH, SLP65, BLNK, B-cell linker protein, B-cell adapter containing a SH2 domain protein, B-cell adapter containing a Src homology 2 domain protein, Cytoplasmic adapter protein, Src homology 2 domain-containing leukocyte protein of 65 kDa, SLP-65

3 Images
Flow Cytometry - Anti-BLNK (phospho Y84) antibody [BLNKY84-H4] (AB278566)
  • Flow Cyt

Supplier Data

Flow Cytometry - Anti-BLNK (phospho Y84) antibody [BLNKY84-H4] (AB278566)

Flow cytometric analysis of Daudi cells secondary antibody only negative control (blue) or untreated (red) or treated with IFNa + IL-4 + pervanadate (green) using 10 ng/mL of ab278566.

Flow Cytometry - Anti-BLNK (phospho Y84) antibody [BLNKY84-H4] (AB278566)
  • Flow Cyt

Supplier Data

Flow Cytometry - Anti-BLNK (phospho Y84) antibody [BLNKY84-H4] (AB278566)

Peptide blocking flow cytometric analysis of Daudi cells secondary antibody only negative control (light blue) or untreated (red) or with IFNa + IL-4 + pervanadate (green) or untreated and blocked with phospho-peptide (black) or treated and blocked with phospho peptide (gold) or untreated and blocked with non-phospho peptide (dark blue) or treated and blocked with non-phospho peptide (purple) using ab278566 at 0.01 µg/mL.

Flow Cytometry - Anti-BLNK (phospho Y84) antibody [BLNKY84-H4] (AB278566)
  • Flow Cyt

Supplier Data

Flow Cytometry - Anti-BLNK (phospho Y84) antibody [BLNKY84-H4] (AB278566)

Flow cytometric analysis of Daudi cells secondary antibody only negative control (blue) or untreated (red) or treated with IFNa + IL-4 + pervanadate (green) using ab278566 at 0.01 µg/mL.

  • 660 APC

    APC Anti-BLNK (phospho Y84) antibody [BLNKY84-H4]

  • 578 PE

    PE Anti-BLNK (phospho Y84) antibody [BLNKY84-H4]

  • 519 FITC

    FITC Anti-BLNK (phospho Y84) antibody [BLNKY84-H4]

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

BLNKY84-H4

Isotype

IgG

Light chain type

kappa

Carrier free

No

Reacts with

Human

Applications

Flow Cyt

applications

Immunogen

Synthetic Peptide within Human BLNK phospho Y84. The exact immunogen used to generate this antibody is proprietary information.

Q8WV28

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "0.00100-1 µg/mL", "FlowCyt-species-notes": "<p></p>" } } }
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Product details

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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A/G
Storage buffer
Preservative: 0.02% Sodium azide Constituents: 50% Glycerol (glycerin, glycerine), 49.88% PBS, 0.1% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Functions as a central linker protein, downstream of the B-cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR-mediated PLCG1 and PLCG2 activation and Ca(2+) mobilization and is required for trafficking of the BCR to late endosomes. However, does not seem to be required for pre-BCR-mediated activation of MAP kinase and phosphatidyl-inositol 3 (PI3) kinase signaling. May be required for the RAC1-JNK pathway. Plays a critical role in orchestrating the pro-B cell to pre-B cell transition. May play an important role in BCR-induced B-cell apoptosis.
See full target information BLNK phospho Y84
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions
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Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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