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AB174837

Anti-BLNK (phospho Y84) antibody [EP2202(2)]

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(2 Publications)

Rabbit Monoclonal BLNK phospho Y84 antibody. Suitable for WB and reacts with Human samples. Cited in 2 publications.

View Alternative Names

BASH, SLP65, BLNK, B-cell linker protein, B-cell adapter containing a SH2 domain protein, B-cell adapter containing a Src homology 2 domain protein, Cytoplasmic adapter protein, Src homology 2 domain-containing leukocyte protein of 65 kDa, SLP-65

1 Images
Western blot - Anti-BLNK (phospho Y84) antibody [EP2202(2)] (AB174837)
  • WB

Supplier Data

Western blot - Anti-BLNK (phospho Y84) antibody [EP2202(2)] (AB174837)

All lanes:

Western blot - Anti-BLNK (phospho Y84) antibody [EP2202(2)] (ab174837) at 1/1000 dilution

Lane 1:

Raji cell lysate, untreated at 10 µg

Lane 2:

Raji cell lysate, treated with pervanadate at 10 µg

Secondary

All lanes:

Goat anti-rabbit HRP at 1/2000 dilution

Predicted band size: 50 kDa

true

  • Carrier free

    Anti-BLNK (phospho Y84) antibody [EP2202(2)] - BSA and Azide free

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EP2202(2)

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

Reactivity data

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Product details

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

Properties and storage information

Form
Liquid
Purity
Tissue culture supernatant
Storage buffer
pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Target data

Functions as a central linker protein, downstream of the B-cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR-mediated PLCG1 and PLCG2 activation and Ca(2+) mobilization and is required for trafficking of the BCR to late endosomes. However, does not seem to be required for pre-BCR-mediated activation of MAP kinase and phosphatidyl-inositol 3 (PI3) kinase signaling. May be required for the RAC1-JNK pathway. Plays a critical role in orchestrating the pro-B cell to pre-B cell transition. May play an important role in BCR-induced B-cell apoptosis.
See full target information BLNK phospho Y84

Publications (2)

Recent publications for all applications. Explore the full list and refine your search

MedComm 4:e348 PubMed37593048

2023

Nucleosome assembly protein 1 like 1 (NAP1L1) promotes cardiac fibrosis by inhibiting YAP1 ubiquitination and degradation.

Applications

Unspecified application

Species

Unspecified reactive species

Tianyu Li,Zhihui Niu,Tong Yu,Jinrui Li,Xin Lu,Mengqin Huang,Qianqian Wang,Xiaojiang Yu,Jiayue Feng,Bingqian Xu,Danyang Bing,Xuelian Li,Lifang Lu,Haihai Liang,Rui Yang,Bin Wang,Hongli Shan

World journal of gastroenterology 28:5865-5880 PubMed36353208

2022

Curcumin alleviates experimental colitis a potential mechanism involving memory B cells and Bcl-6-Syk-BLNK signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Si-Yi Wei,Tian-Tian Wu,Jia-Qi Huang,Zeng-Ping Kang,Meng-Xue Wang,You-Bao Zhong,Wei Ge,Bu-Gao Zhou,Hai-Mei Zhao,Hai-Yan Wang,Duan-Yong Liu
View all publications

Product promise

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