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AB38953

Anti-BMP1/PCP antibody

5

(3 Reviews)

|

(6 Publications)

Rabbit Polyclonal BMP1/PCP antibody. Suitable for WB and reacts with Mouse, Human samples. Cited in 6 publications. Immunogen corresponding to Synthetic Peptide within Human BMP1.

View Alternative Names

PCOLC, BMP1, Bone morphogenetic protein 1, BMP-1, Mammalian tolloid protein, Procollagen C-proteinase, mTld, PCP

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human, Mouse

Applications

WB

applications

Immunogen

Synthetic Peptide within Human BMP1. The exact immunogen used to generate this antibody is proprietary information.

P13497

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p>A recommended starting concentration for Western blots is 1/1000 when using colorimetric substrates such as BCIP/NBT and 1/5000 for chemiluminescent substrates. EDTA/EGTA treatment of tissues or lysates is required to see latent zymogen.</p>" }, "Mouse": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p>A recommended starting concentration for Western blots is 1/1000 when using colorimetric substrates such as BCIP/NBT and 1/5000 for chemiluminescent substrates. EDTA/EGTA treatment of tissues or lysates is required to see latent zymogen.</p>" } } }

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Purification notes
ab38953 has been peptide-affinity purified.
Storage buffer
Preservative: 0.01% Sodium azide Constituents: 50% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Target data

Metalloprotease that plays key roles in regulating the formation of the extracellular matrix (ECM) via processing of various precursor proteins into mature functional enzymes or structural proteins (PubMed : 33206546). Thereby participates in several developmental and physiological processes such as cartilage and bone formation, muscle growth and homeostasis, wound healing and tissue repair (PubMed : 32636307, PubMed : 33169406). Roles in ECM formation include cleavage of the C-terminal propeptides from procollagens such as procollagen I, II and III or the proteolytic activation of the enzyme lysyl oxidase LOX, necessary to formation of covalent cross-links in collagen and elastic fibers (PubMed : 31152061, PubMed : 33206546). Additional substrates include matricellular thrombospondin-1/THBS1 whose cleavage leads to cell adhesion disruption and TGF-beta activation (PubMed : 32636307).. Isoform BMP1-3. Plays an important role in bone repair by acting as a coactivator of BMP7.
See full target information BMP1

Publications (6)

Recent publications for all applications. Explore the full list and refine your search

Scientific reports 14:15998 PubMed38987293

2024

Human amniotic membrane modulates collagen production and deposition in vitro.

Applications

Unspecified application

Species

Unspecified reactive species

Sarah E Moreno,Isioma Enwerem-Lackland,Kristiana Dreaden,Michelle Massee,Thomas J Koob,John R Harper

Physiological reports 8:e14436 PubMed32533648

2020

Elastin homeostasis is altered with pelvic organ prolapse in cultures of vaginal cells from a lysyl oxidase-like 1 knockout mouse model.

Applications

Unspecified application

Species

Unspecified reactive species

Slater A Jameson,Ganesh Swaminathan,Shataakshi Dahal,Bruna Couri,Mei Kuang,Anna Rietsch,Robert S Butler,Anand Ramamurthi,Margot S Damaser

Genome biology 21:64 PubMed32160911

2020

Smarcad1 mediates microbiota-induced inflammation in mouse and coordinates gene expression in the intestinal epithelium.

Applications

Unspecified application

Species

Unspecified reactive species

Juri Kazakevych,Jérémy Denizot,Anke Liebert,Mariana Portovedo,Mia Mosavie,Payal Jain,Claudia Stellato,Claire Fraser,Renan Oliveira Corrêa,Marina Célestine,Raphaël Mattiuz,Hanneke Okkenhaug,J Ross Miller,Marco Aurélio Ramirez Vinolo,Marc Veldhoen,Patrick Varga-Weisz

Journal of molecular and cellular cardiology 85:229-39 PubMed26080361

2015

Building a better infarct: Modulation of collagen cross-linking to increase infarct stiffness and reduce left ventricular dilation post-myocardial infarction.

Applications

Unspecified application

Species

Unspecified reactive species

Andrew P Voorhees,Kristine Y DeLeon-Pennell,Yonggang Ma,Ganesh V Halade,Andriy Yabluchanskiy,Rugmani Padmanabhan Iyer,Elizabeth Flynn,Courtney A Cates,Merry L Lindsey,Hai-Chao Han

American journal of physiology. Heart and circulat 300:H1418-26 PubMed21297029

2011

CC chemokine receptor 5 deletion impairs macrophage activation and induces adverse remodeling following myocardial infarction.

Applications

WB

Species

Mouse

Rogelio Zamilpa,Rushit Kanakia,Joaquin Cigarroa,Qiuxia Dai,G Patricia Escobar,Hernan Martinez,Fabio Jimenez,Seema S Ahuja,Merry L Lindsey

Molecules and cells 29:123-30 PubMed20016938

2009

Mining of serum glycoproteins by an indirect approach using cell line secretome.

Applications

WB

Species

Human

Younghee Ahn,Un-Beom Kang,Joon Kim,Cheolju Lee
View all publications

Product promise

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