AB264043

Anti-BMPR1A antibody

Name: Anti-BMPR1A antibody (ab264043) | Abcam
Brand: Abcam Limited
SKU: AB264043
Price: 525 USD
Availability: InStock

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(9 Publications)

Rabbit Polyclonal BMPR1A antibody. Suitable for Flow Cyt, WB, IHC-P and reacts with Human, Mouse, Rat samples. Cited in 9 publications. Immunogen corresponding to Synthetic Peptide within Human BMPR1A aa 50-150 conjugated to Keyhole Limpet Haemocyanin.

View Alternative Names

CD292, ACVRLK3, ALK3, BMPR1A, Bone morphogenetic protein receptor type-1A, BMP type-1A receptor, BMPR-1A, Activin receptor-like kinase 3, Serine/threonine-protein kinase receptor R5, ALK-3, SKR5

3 Images

Flow Cytometry - Anti-BMPR1A antibody (AB264043)

Flow Cyt

Supplier Data

Flow Cytometry - Anti-BMPR1A antibody (AB264043)

HCCLM3 (human hepatocellular carconoma cell line) cells labeling BMPR1A using ab264043 at 1/20 dilution for 30 minutes, followed by an FITC-conjugated secondary antibody (green line) as compared to control cells (dark blue line), secondary antibody only (light blue line) and an isotype control (orange line).

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BMPR1A antibody (AB264043)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BMPR1A antibody (AB264043)

Formalin-fixed, paraffin-embedded rat bone marrow tissue staining BMPR1A using ab264043 at a 1/200 dilution. DAB staining.

Supplier Data

Western blot - Anti-BMPR1A antibody (AB264043)

Primary incubation overnight at 4°C.

Secondary incubation for 90 minutes at 37°C.

All lanes:

Western blot - Anti-BMPR1A antibody (ab264043) at 1/200 dilution

Lane 1:

Rat brain lysate

Lane 2:

Mouse brain lysate

Secondary

All lanes:

HRP-conjugated secondary antibody at 1/3000 dilution

Predicted band size: 60 kDa

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Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Mouse, Rat, Human

Applications

Flow Cyt, IHC-P, WB

applications

Immunogen

Synthetic Peptide within Human BMPR1A aa 50-150 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.

P36894

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "1/20 - 1/100", "FlowCyt-species-notes": "", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Mouse": { "FlowCyt-species-checked": "guaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/300 - 1/1000", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "FlowCyt-species-checked": "guaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/300 - 1/1000", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/200 - 1/400", "IHCP-species-notes": "" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein A

Storage buffer

pH: 7.4 Preservative: 0.02% Proclin 300 Constituents: 50% Glycerol (glycerin, glycerine), 48.98% TBS, 1X, 1% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6. May promote the expression of HAMP, potentially via its interaction with BMP2 (By similarity).

See full target information BMPR1A

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Publications (9)

Recent publications for all applications. Explore the full list and refine your search

Bioactive materials 48:242-256 PubMed40046012

2025

An axolotl limb regeneration-inspired strategy to enhance alveolar bone regeneration.

Applications

Unspecified application

Species

Unspecified reactive species

Rongpu Liu,Guifang Wang,Li Ma,Guangzheng Yang,Sihan Lin,Ningjia Sun,Jiajia Wang,Huijing Ma,Xinquan Jiang,Wenjie Zhang

The clinical respiratory journal 18:e13770 PubMed38783645

2024

ZEB1-AS1 mediates bone metastasis through targeting miR-320b/BMPR1A axis in lung cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Nianxi Tan,Junyi Tang,Guang Chen,Weilin Jiang,Zhiqin Liu

Nature communications 14:7541 PubMed38001081

2023

Autophagy drives the conversion of developmental neural stem cells to the adult quiescent state.

Applications

Unspecified application

Species

Unspecified reactive species

Isabel Calatayud-Baselga,Lucía Casares-Crespo,Carmina Franch-Ibáñez,José Guijarro-Nuez,Pascual Sanz,Helena Mira

Regenerative therapy 24:351-360 PubMed37674692

2023

Acyl-protein thioesterase1 alleviates senile osteoporosis by promoting osteoblast differentiation via depalmitoylation of BMPR1a.

Applications

Unspecified application

Species

Unspecified reactive species

Changjiao Ji,Qiaoyan Dong,Huihui Liu,Xiaodeng Yang,Yingguang Han,Bingrui Zhu,Huaixin Xing

Bone & joint research 12:397-411 PubMed37394235

2023

Multiple roles of ALK3 in osteoarthritis.

Applications

Unspecified application

Species

Unspecified reactive species

Xianchun Ruan,Jinning Gu,Mingyang Chen,Fulin Zhao,Munire Aili,Demao Zhang

Stem cell research & therapy 14:130 PubMed37189178

2023

Epithelium-derived SCUBE3 promotes polarized odontoblastic differentiation of dental mesenchymal stem cells and pulp regeneration.

Applications

Unspecified application

Species

Unspecified reactive species

Zijie Wang,Chuying Chen,Jiayi Zhang,Jiangdie He,Lin Zhang,Jiayuan Wu,Zhihui Tian

Scientific reports 12:15968 PubMed36153352

2022

FGF receptor inhibitor BGJ398 partially rescues osteoarthritis-like phenotype in older high molecular weight FGF2 transgenic mice via multiple mechanisms.

Applications

Unspecified application

Species

Unspecified reactive species

Marja M Hurley,J Douglas Coffin,Thomas Doetschman,Christina Valera,Kai Clarke,Liping Xiao

International journal of biological sciences 17:2367-2379 PubMed34239363

2021

Recombinant human bone morphogenetic protein 2 and 7 inhibit the degeneration of intervertebral discs by blocking the Puma-dependent apoptotic signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Shiwei Xie,Chenyang Zhao,Wei Chen,Gengwu Li,Zhiwei Xiong,Xiangjun Tang,Fan Zhang,Heng Xiao

Science translational medicine 13: PubMed33658353

2021

BMPR1A maintains skeletal stem cell properties in craniofacial development and craniosynostosis.

Applications

Unspecified application

Species

Unspecified reactive species

Takamitsu Maruyama,Ronay Stevens,Alan Boka,Laura DiRienzo,Connie Chang,Hsiao-Man Ivy Yu,Katsuhiko Nishimori,Clinton Morrison,Wei Hsu

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-BMPR1A antibody

Flow Cytometry - Anti-BMPR1A antibody (AB264043)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BMPR1A antibody (AB264043)

Western blot - Anti-BMPR1A antibody (AB264043)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (9)

Complementary Products

Secondary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Product promise