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Mouse Monoclonal BMPR1B antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 7 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human BMPR1B.

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Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BMPR1B antibody [MM0055-3E12] (AB78417), expandable thumbnail
  • Western blot - Anti-BMPR1B antibody [MM0055-3E12] (AB78417), expandable thumbnail

Publications

Key facts

Isotype

IgG2a

Host species

Mouse

Storage buffer

Constituents: PBS

Form

Liquid

Clonality

Monoclonal

Immunogen

  • Recombinant Full Length Protein corresponding to Human BMPR1B. Database link O00238

Reactivity data

Select an application
Product promiseTestedExpectedPredictedNot recommended
WBIHC-P
Human
Tested
Tested

Tested
Tested

Species

Human

Dilution info

1/100 - 1/1000

Notes

-

Tested
Tested

Species

Human

Dilution info

1/50 - 1/200

Notes

-

Associated Products

Select an associated product type

1 products for Alternative Product

Target data

Function

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP7/OP-1 and GDF5. Positively regulates chondrocyte differentiation through GDF5 interaction.

Alternative names

Bone morphogenetic protein receptor type-1B, BMP type-1B receptor, BMPR-1B, BMPR1B

Recommended products

Mouse Monoclonal BMPR1B antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 7 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human BMPR1B.

Alternative names

Bone morphogenetic protein receptor type-1B, BMP type-1B receptor, BMPR-1B, BMPR1B

Key facts

Isotype

IgG2a

Form

Liquid

Clonality

Monoclonal

Immunogen
  • Recombinant Full Length Protein corresponding to Human BMPR1B. Database link O00238
Clone number

MM0055-3E12

Purification technique

Affinity purification Protein G

Specificity

ab78417 detects BMPR1B. No cross reactivity was found to BMPR1A (ALK3).

Concentration
Loading...
Purification notes

The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and lyophilized from a 0.2 µm filtered solution inphosphate buffered saline (PBS).

Storage

Shipped at conditions

Blue Ice

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

Notes

Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.

If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.

Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.

Product promise

We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.

In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
Terms & Conditions.

2 product images

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BMPR1B antibody [MM0055-3E12] (ab78417), expandable thumbnail

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BMPR1B antibody [MM0055-3E12] (ab78417)

    ab78417 at 1/200 dilution staining BMPR1B in human placental tissue section by Immunohistochemistry (Formalin/PFA fixed paraffin-embedded sections).

  • Western blot - Anti-BMPR1B antibody [MM0055-3E12] (ab78417), expandable thumbnail

    Western blot - Anti-BMPR1B antibody [MM0055-3E12] (ab78417)

    The band observed at 53 kDa could potentially be a cleaved form of BMPR1B due to presence of a 13 amino acid signal peptide.

    All lanes: Western blot - Anti-BMPR1B antibody [MM0055-3E12] (ab78417) at 1 µg/mL

    Lane 1: Human bone tumor tissue lysate - total protein (ab29359) at 10 µg

    Lane 2: WI38 (Human lung fibroblast cell line) Whole Cell Lysate at 10 µg

    Secondary

    All lanes: Western blot - Goat Anti-Mouse IgG H&L (HRP) preadsorbed (Goat Anti-Mouse IgG H&L (HRP) preadsorbed ab97040) at 1/5000 dilution

    Developed using the ECL technique.

    Performed under reducing conditions.

    Predicted band size: 57 kDa

    Observed band size: 30 kDa, 37 kDa, 50 kDa, 57 kDa

    Exposure time: 30s

Downloads

Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

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