AB106266

Anti-BMPR2 antibody

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(4 Publications)

Rabbit Polyclonal BMPR2 antibody. Suitable for WB and reacts with Human samples. Cited in 4 publications. Immunogen corresponding to Recombinant Fragment Protein within Human BMPR2 aa 250-600.

View Alternative Names

PPH1, BMPR2, Bone morphogenetic protein receptor type-2, BMP type-2 receptor, BMPR-2, Bone morphogenetic protein receptor type II, BMP type II receptor, BMPR-II

1 Images

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Western blot - Anti-BMPR2 antibody (AB106266)

All lanes:

Western blot - Anti-BMPR2 antibody (ab106266) at 1/500 dilution

All lanes:

Raji cell lysate

Predicted band size: 115 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

applications

Immunogen

Recombinant Fragment Protein within Human BMPR2 aa 250-600. The exact immunogen used to generate this antibody is proprietary information.

Q13873

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/1000", "WB-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }

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Properties and storage information

Form

Lyophilized

Reconstitution

Reconstitute in 200 µL of water

Purification technique

Affinity purification Immunogen

Storage buffer

pH: 7.2 Preservative: 0.02% Sodium azide Constituents: 1% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Can also mediate signaling through the activation of the p38MAPK cascade (PubMed : 12045205). Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6. Promotes signaling also by binding to activin A/INHBA (PubMed : 24018044).

See full target information BMPR2

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Publications (4)

Recent publications for all applications. Explore the full list and refine your search

Cell cycle (Georgetown, Tex.) 18:1714-1726 PubMed31234714

2019

Gremlin is a potential target for posterior capsular opacification.

Applications

Unspecified application

Species

Unspecified reactive species

Bo Ma,Ruihua Jing,Jie Liu,Tiantian Qi,Cheng Pei

Circulation research 116:857-66 PubMed25587097

2015

Endocardial fibroelastosis is caused by aberrant endothelial to mesenchymal transition.

Applications

Unspecified application

Species

Unspecified reactive species

Xingbo Xu,Ingeborg Friehs,Tachi Zhong Hu,Ivan Melnychenko,Björn Tampe,Fouzi Alnour,Maria Iascone,Raghu Kalluri,Michael Zeisberg,Pedro J Del Nido,Elisabeth M Zeisberg

The Journal of cell biology 206:799-811 PubMed25202030

2014

Activation of RhoA-ROCK-BMP signaling reprograms adult human corneal endothelial cells.

Applications

Unspecified application

Species

Human

Ying-Ting Zhu,Fu Li,Bo Han,Sean Tighe,Suzhen Zhang,Szu-Yu Chen,Xin Liu,Scheffer C G Tseng

PloS one 9:e89114 PubMed24586530

2014

Bone morphogenetic protein signaling protects against cerulein-induced pancreatic fibrosis.

Applications

Unspecified application

Species

Mouse

Xuxia Gao,Yanna Cao,Dustin A Staloch,Michael A Gonzales,Judith F Aronson,Celia Chao,Mark R Hellmich,Tien C Ko

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-BMPR2 antibody

Western blot - Anti-BMPR2 antibody (AB106266)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

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Reactivity data

Properties and storage information

Form

Reconstitution

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (4)

Product promise