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AB20984

Anti-BNP antibody [50E1]

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(5 Publications)

Mouse Monoclonal BNP antibody. Suitable for ELISA, WB, sELISA, ICC/IF and reacts with Human samples. Cited in 5 publications.

View Alternative Names

Natriuretic peptides B, Brain natriuretic factor prohormone, Gamma-brain natriuretic peptide, Iso-ANP, preproBNP, proBNP, NPPB

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

50E1

Isotype

IgG1

Carrier free

No

Reacts with

Human

Applications

sELISA, ELISA, WB, ICC/IF

applications

Epitope

ab20984 binds to epitope aa 26-32 of Brain natriuretic peptide 32 (CKVLRRH).

Specificity

ab20984 detects Human BNP and proBNP.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "sELISA" : {"fullname" : "Sandwich ELISA", "shortname":"sELISA"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p></p>", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>", "sELISA-species-checked": "guaranteed", "sELISA-species-dilution-info": "", "sELISA-species-notes": "<p>Can be used as capture antibody</p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>" } } }
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Product details

This product has switched from ascites to TCS on 29th June 2020. Stock up to lot GR3225984 has been generated from ascites.
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
pH: 7.4 Preservative: 0.1% Sodium azide Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Brain natriuretic peptide 32. Cardiac hormone that plays a key role in mediating cardio-renal homeostasis (PubMed : 1672777, PubMed : 17372040, PubMed : 1914098, PubMed : 9458824). May also function as a paracrine antifibrotic factor in the heart (By similarity). Acts by specifically binding and stimulating NPR1 to produce cGMP, which in turn activates effector proteins that drive various biological responses (PubMed : 1672777, PubMed : 17349887, PubMed : 17372040, PubMed : 21098034, PubMed : 25339504, PubMed : 9458824). Involved in regulating the extracellular fluid volume and maintaining the fluid-electrolyte balance through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion (PubMed : 1914098, PubMed : 9458824). Binds the clearance receptor NPR3 (PubMed : 16870210).. NT-proBNP. May affect cardio-renal homeostasis (PubMed : 17372040). Able to promote the production of cGMP although its potency is very low compared to brain natriuretic peptide 32 (PubMed : 17372040).. BNP(3-32). May have a role in cardio-renal homeostasis (PubMed : 17372040). Able to promote the production of cGMP (PubMed : 17372040).
See full target information NPPB
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Publications (5)

Recent publications for all applications. Explore the full list and refine your search

Microbiome 12:157 PubMed39182099

2024

BCAA mediated microbiota-liver-heart crosstalk regulates diabetic cardiomyopathy via FGF21.

Applications

Unspecified application

Species

Unspecified reactive species

Hong Zheng,Xi Zhang,Chen Li,Die Wang,Yuying Shen,Jiahui Lu,Liangcai Zhao,Xiaokun Li,Hongchang Gao

Microsystems & nanoengineering 7:51 PubMed34567764

2021

Low limit of detection of the AlGaN/GaN-based sensor by the Kelvin connection detection technique.

Applications

Unspecified application

Species

Unspecified reactive species

Hanyuan Zhang,Ying Gan,Shu Yang,Kuang Sheng,Ping Wang

International journal of nanomedicine 12:4455-4466 PubMed28670119

2017

Improved LFIAs for highly sensitive detection of BNP at point-of-care.

Applications

Unspecified application

Species

Unspecified reactive species

Yan Gong,Jie Hu,Jane Ru Choi,Minli You,Yamin Zheng,Bo Xu,Ting Wen,Feng Xu

American journal of physiology. Heart and circulatory physiology 310:H290-9 PubMed26566724

2015

Cardiac remodeling in the mouse model of Marfan syndrome develops into two distinctive phenotypes.

Applications

Unspecified application

Species

Unspecified reactive species

Hyun-Jin Tae,Natalia Petrashevskaya,Shannon Marshall,Melissa Krawczyk,Mark Talan

Clinical chemistry 57:864-73 PubMed21482747

2011

Secretion of glycosylated pro-B-type natriuretic peptide from normal cardiomyocytes.

Applications

WB, ICC/IF

Species

Human, Human

Jason M Tonne,Jarryd M Campbell,Alessandro Cataliotti,Seiga Ohmine,Tayaramma Thatava,Toshie Sakuma,Fima Macheret,Brenda K Huntley,John C Burnett,Yasuhiro Ikeda
View all publications
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Product promise

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