AB19645

Anti-BNP antibody

Name: Anti-BNP antibody. Rabbit polyclonal (ab19645) | Abcam
Brand: Abcam Limited
SKU: AB19645
Price: 595 USD
Availability: InStock
Rating: 5 (2 reviews)

(2 Reviews)

(47 Publications)

Rabbit Polyclonal BNP antibody. Suitable for WB and reacts with Human, Rat samples. Cited in 47 publications.

View Alternative Names

Natriuretic peptides B, Brain natriuretic factor prohormone, Gamma-brain natriuretic peptide, Iso-ANP, preproBNP, proBNP, NPPB

1 Images

Unknown

Western blot - Anti-BNP antibody (AB19645)

All lanes:

Western blot - Anti-BNP antibody (ab19645) at 1/500 dilution

Lane 1:

SK N BE (Human neuroblastoma) Whole Cell Lysate at 10 µg

Lane 2:

TE 671 (Human Rhabdomyosarcoma) Whole Cell Lysate at 10 µg

Lane 3:

SW480 (Human colon adenocarcinoma cell line) Whole Cell Lysate at 10 µg

Secondary

All lanes:

Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution

Predicted band size: 15 kDa

Observed band size: 18 kDa,40 kDa,48 kDa,60 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Rat, Human

Applications

applications

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500", "WB-species-notes": "<p></p>" }, "Rat": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "1/500", "WB-species-notes": "<p></p>" } } }

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Properties and storage information

Form

Liquid

Purity

Whole antiserum

Storage buffer

Constituents: PBS, 1% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Brain natriuretic peptide 32. Cardiac hormone that plays a key role in mediating cardio-renal homeostasis (PubMed : 1672777, PubMed : 17372040, PubMed : 1914098, PubMed : 9458824). May also function as a paracrine antifibrotic factor in the heart (By similarity). Acts by specifically binding and stimulating NPR1 to produce cGMP, which in turn activates effector proteins that drive various biological responses (PubMed : 1672777, PubMed : 17349887, PubMed : 17372040, PubMed : 21098034, PubMed : 25339504, PubMed : 9458824). Involved in regulating the extracellular fluid volume and maintaining the fluid-electrolyte balance through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion (PubMed : 1914098, PubMed : 9458824). Binds the clearance receptor NPR3 (PubMed : 16870210).. NT-proBNP. May affect cardio-renal homeostasis (PubMed : 17372040). Able to promote the production of cGMP although its potency is very low compared to brain natriuretic peptide 32 (PubMed : 17372040).. BNP(3-32). May have a role in cardio-renal homeostasis (PubMed : 17372040). Able to promote the production of cGMP (PubMed : 17372040).

See full target information NPPB

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Publications (47)

Recent publications for all applications. Explore the full list and refine your search

Cellular and molecular life sciences : CMLS 82:269 PubMed40610735

2025

Cell division cycle protein 42-driven activation of the MKK3/6-p38 signaling pathway participates in cardiac remodeling in mice.

Applications

Unspecified application

Species

Unspecified reactive species

Ke Wen,Lin Xie,Quan-Wen Liu,Guan-Hui Yu,Xu-Hui Qiao,Yu-Chun Huang,Lu Wang,Xin Li,Li-Dan Wen,Xiao-Lei Wang,Jing He,Xin-Yu Xiao,Xiao-Xiao Zhao,Ling-Fang Wang,Hong-Bo Xin,Ke-Yu Deng

British journal of pharmacology 182:2897-2913 PubMed40097259

2025

TLR2 activates AP-1 to facilitate CTGF transcription and stimulate doxorubicin-induced myocardial injury.

Applications

Unspecified application

Species

Unspecified reactive species

Lang Hong,Xinyong Cai,Yuliang Zhan,Songtao Liu,Pengtao Zou,Yanmei Chen,Liang Shao

Molecular metabolism 86:101970 PubMed38908792

2024

Limiting extracellular matrix expansion in diet-induced obese mice reduces cardiac insulin resistance and prevents myocardial remodelling.

Applications

Unspecified application

Species

Unspecified reactive species

Vishal Musale,Colin E Murdoch,Ayman K Banah,Annie Hasib,Chandani K Hennayake,Bo Dong,Chim C Lang,David H Wasserman,Li Kang

Cell death & disease 15:406 PubMed38858351

2024

Histone acetyltransferase Kat2a regulates ferroptosis via enhancing Tfrc and Hmox1 expression in diabetic cardiomyopathy.

Applications

Unspecified application

Species

Unspecified reactive species

Juan Zhen,Xia Sheng,Tianlong Chen,Haitao Yu

International heart journal 65:475-486 PubMed38825493

2024

Aspirin and Celecoxib Regulate Notch1/Hes1 Pathway to Prevent Pressure Overload-Induced Myocardial Hypertrophy.

Applications

Unspecified application

Species

Unspecified reactive species

Minghui Wei,Ziyu Lu,Haifeng Zhang,Xiaomei Fan,Xin Zhang,Bihui Jiang,Jianying Li,Mingming Xue

ESC heart failure 11:1580-1593 PubMed38369950

2024

Chlorogenic acid attenuates cardiac hypertrophy via up-regulating Sphingosine-1-phosphate receptor1 to inhibit endoplasmic reticulum stress.

Applications

Unspecified application

Species

Unspecified reactive species

Ping Ping,Ting Yang,Chaoxue Ning,Qingkai Zhao,Yali Zhao,Tao Yang,Zhitao Gao,Shihui Fu

ACS pharmacology & translational science 6:1129-1142 PubMed37588762

2023

β-Caryophyllene, a Dietary Phytocannabinoid, Alleviates Diabetic Cardiomyopathy in Mice by Inhibiting Oxidative Stress and Inflammation Activating Cannabinoid Type-2 Receptors.

Applications

Unspecified application

Species

Unspecified reactive species

Hebaallah Mamdouh Hashiesh,Azimullah Sheikh,Mohamed Fizur Nagoor Meeran,Dhanya Saraswathiamma,Niraj Kumar Jha,Bassem Sadek,Ernest Adeghate,Saeed Tariq,Saeeda Al Marzooqi,Shreesh Ojha

Antioxidants (Basel, Switzerland) 12: PubMed37237888

2023

Osthole Prevents Heart Damage Induced by Diet-Induced Metabolic Syndrome: Role of Fructokinase (KHK).

Applications

Unspecified application

Species

Unspecified reactive species

Fernando E García-Arroyo,Guillermo Gonzaga-Sánchez,Alejandro Silva-Palacios,Francisco Javier Roldán,María L Loredo-Mendoza,Yamnia Quetzal Alvarez-Alvarez,Jesus A de Los Santos Coyotl,Kevin A Vélez Orozco,Edilia Tapia,Horacio Osorio-Alonso,Abraham S Arellano-Buendía,José L Sánchez-Gloria,Miguel A Lanaspa,Richard J Johnson,Laura Gabriela Sánchez-Lozada

European journal of histochemistry : EJH 66: PubMed35726535

2022

MALAT1 regulates hypertrophy of cardiomyocytes by modulating the miR-181a/HMGB2 pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Feng Chen,Wenfeng Li,Dandan Zhang,Youlin Fu,Wenjin Yuan,Gang Luo,Fuwei Liu,Jun Luo

Clinical and translational medicine 12:e574 PubMed35390228

2022

Bmi-1-RING1B prevents GATA4-dependent senescence-associated pathological cardiac hypertrophy by promoting autophagic degradation of GATA4.

Applications

Unspecified application

Species

Unspecified reactive species

Haiyun Chen,Jiawen Zhou,Hongjie Chen,Jialong Liang,Chunfeng Xie,Xin Gu,Rong Wang,Zhiyuan Mao,Yongjie Zhang,Qing Li,Guoping Zuo,Dengshun Miao,Jianliang Jin

View all publications

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