Rabbit Polyclonal BNP antibody. Suitable for WB and reacts with Human, Rat samples. Cited in 37 publications.
Constituents: PBS, 1% BSA
WB | |
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Human | Tested |
Rat | Expected |
Species | Dilution info | Notes |
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Species Human | Dilution info 1/500 | Notes - |
Species | Dilution info | Notes |
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Species Rat | Dilution info 1/500 | Notes - |
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Brain natriuretic peptide 32. Cardiac hormone that plays a key role in mediating cardio-renal homeostasis (PubMed:1672777, PubMed:17372040, PubMed:1914098, PubMed:9458824). May also function as a paracrine antifibrotic factor in the heart (By similarity). Acts by specifically binding and stimulating NPR1 to produce cGMP, which in turn activates effector proteins that drive various biological responses (PubMed:1672777, PubMed:17349887, PubMed:17372040, PubMed:21098034, PubMed:25339504, PubMed:9458824). Involved in regulating the extracellular fluid volume and maintaining the fluid-electrolyte balance through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion (PubMed:1914098, PubMed:9458824). Binds the clearance receptor NPR3 (PubMed:16870210). NT-proBNP. May affect cardio-renal homeostasis (PubMed:17372040). Able to promote the production of cGMP although its potency is very low compared to brain natriuretic peptide 32 (PubMed:17372040). BNP(3-32). May have a role in cardio-renal homeostasis (PubMed:17372040). Able to promote the production of cGMP (PubMed:17372040).
Natriuretic peptides B, Brain natriuretic factor prohormone, Gamma-brain natriuretic peptide, Iso-ANP, preproBNP, proBNP, NPPB
Rabbit Polyclonal BNP antibody. Suitable for WB and reacts with Human, Rat samples. Cited in 37 publications.
Constituents: PBS, 1% BSA
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This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
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All lanes: Western blot - Anti-BNP antibody (ab19645) at 1/500 dilution
Lane 1: SK N BE (Human neuroblastoma) Whole Cell Lysate at 10 µg
Lane 2: TE 671 (Human Rhabdomyosarcoma) Whole Cell Lysate at 10 µg
Lane 3: SW480 (Human colon adenocarcinoma cell line) Whole Cell Lysate at 10 µg
All lanes: Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
Predicted band size: 15 kDa
Observed band size: 18 kDa, 40 kDa, 48 kDa, 60 kDa
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