AB183337

Anti-BRAF antibody [pBR1]

Name: Anti-BRAF antibody [pBR1] (ab183337) | Abcam
Brand: Abcam Limited
SKU: AB183337
Price: 215 USD
Availability: InStock

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(1 Publication)

Rat Monoclonal BRAF antibody. Suitable for IHC-P and reacts with Human samples. Cited in 1 publication.

View Alternative Names

BRAF1, RAFB1, BRAF, Serine/threonine-protein kinase B-raf, Proto-oncogene B-Raf, p94, v-Raf murine sarcoma viral oncogene homolog B1

1 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BRAF antibody [pBR1] (AB183337)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BRAF antibody [pBR1] (AB183337)

Immunohistochemical analysis of paraffin-embedded Human colon carcinoma tissue labeling B Raf with ab183337 at 1/100 dilution.

Key facts

Host species

Rat

Clonality

Monoclonal

Clone number

pBR1

Isotype

IgG2a

Carrier free

Reacts with

Human

Applications

IHC-P

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/100", "IHCP-species-notes": "<p>Boil tissue section in EDTA buffer pH 8.0 for 10 min followed by cooling at room temperature for 20 min.</p>" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein A/G

Purification notes

Protein A/G purified.

Storage buffer

pH: 7.6 Preservative: 0.1% Sodium azide Constituents: PBS, 1% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus (Probable). Phosphorylates MAP2K1, and thereby activates the MAP kinase signal transduction pathway (PubMed : 21441910, PubMed : 29433126). Phosphorylates PFKFB2 (PubMed : 36402789). May play a role in the postsynaptic responses of hippocampal neurons (PubMed : 1508179).

See full target information BRAF

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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Cancer 119:2765-70 PubMed23657789

2013

Mutation-specific antibody detects mutant BRAFV600E protein expression in human colon carcinomas.

Applications

Unspecified application

Species

Unspecified reactive species

Frank A Sinicrope,Thomas C Smyrk,David Tougeron,Stephen N Thibodeau,Shalini Singh,Andrea Muranyi,Kandavel Shanmugam,Thomas M Grogan,Steven R Alberts,Qian Shi

View all publications

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Product promise

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