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AB314048

Anti-BRD7 antibody [BLR221K] - BSA free

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Rabbit Recombinant Monoclonal BRD7 antibody. Suitable for Flow Cyt, ICC, IHC-P, IP, WB and reacts with Human samples. Immunogen corresponding to Synthetic Peptide within Human BRD7 aa 600 to C-terminus.

View Alternative Names

BP75, CELTIX1, BRD7, Bromodomain-containing protein 7, 75 kDa bromodomain protein, Protein CELTIX-1

4 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BRD7 antibody [BLR221K] - BSA free (AB314048)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BRD7 antibody [BLR221K] - BSA free (AB314048)

Sample : FFPE section of human testis. Antibody : Rabbit anti-BRD7 recombinant monoclonal antibody [BLR221K] (A700-221-1). Secondary : HRP-conjugated goat antirabbit IgG (A120-501P).

Immunocytochemistry - Anti-BRD7 antibody [BLR221K] - BSA free (AB314048)
  • ICC

Supplier Data

Immunocytochemistry - Anti-BRD7 antibody [BLR221K] - BSA free (AB314048)

Sample : FFPE section of RKO cells. Antibody : Rabbit antiBRD7 recombinant monoclonal antibody [BLR221K] Secondary : HRP-conjugated goat antirabbit IgG

Flow Cytometry - Anti-BRD7 antibody [BLR221K] - BSA free (AB314048)
  • Flow Cyt

Supplier Data

Flow Cytometry - Anti-BRD7 antibody [BLR221K] - BSA free (AB314048)

Antibody : Rabbit anti-BRD7 recombinant monoclonal antibody [BLR221K] or isotype control (unshaded). Secondary : DyLight® 650-conjugated goat anti-rabbit IgG

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BRD7 antibody [BLR221K] - BSA free (AB314048)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BRD7 antibody [BLR221K] - BSA free (AB314048)

Sample : FFPE section of prostate carcinoma. Antibody : Rabbit anti-BRD7 recombinant monoclonal antibody [BLR221K]. Secondary : HRP-conjugated goat anti-rabbit IgG

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

BLR221K

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IP, ICC, IHC-P, Flow Cyt, WB

applications

Immunogen

Synthetic Peptide within Human BRD7 aa 600 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q9NPI1

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"}, "ICC" : {"fullname" : "Immunocytochemistry", "shortname":"ICC"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p></p>", "ICC-species-checked": "testedAndGuaranteed", "ICC-species-dilution-info": "", "ICC-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "IP-species-checked": "testedAndGuaranteed", "IP-species-dilution-info": "", "IP-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>" } } }
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Product details

REACH authorisation
Abcam has not and does not intend to apply for the REACH Authorisation of customers' uses of products that contain European Authorisation list (Annex XIV) substances.
It is the responsibility of our customers to check the necessity of application of REACH Authorisation, and any other relevant authorisations, for their intended uses.
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Properties and storage information

Form
Liquid
Storage buffer
pH: 7.8 - 8.6 Preservative: 0.09% Sodium azide Constituents: 98% Borate buffered saline
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
Up to 12 months
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Acts both as coactivator and as corepressor. May play a role in chromatin remodeling. Activator of the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. Induces dephosphorylation of GSK3B at 'Tyr-216'. Down-regulates TRIM24-mediated activation of transcriptional activation by AR (By similarity). Transcriptional corepressor that down-regulates the expression of target genes. Binds to target promoters, leading to increased histone H3 acetylation at 'Lys-9' (H3K9ac). Binds to the ESR1 promoter. Recruits BRCA1 and POU2F1 to the ESR1 promoter. Coactivator for TP53-mediated activation of transcription of a set of target genes. Required for TP53-mediated cell-cycle arrest in response to oncogene activation. Promotes acetylation of TP53 at 'Lys-382', and thereby promotes efficient recruitment of TP53 to target promoters. Inhibits cell cycle progression from G1 to S phase.
See full target information BRD7
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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