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AB227086

Anti-BS69 antibody

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(2 Publications)

Rabbit Polyclonal BS69 antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human ZMYND11.

View Alternative Names

BRAM1, BS69, ZMYND11, Zinc finger MYND domain-containing protein 11, Adenovirus 5 E1A-binding protein, Bone morphogenetic protein receptor-associated molecule 1, Protein BS69

3 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BS69 antibody (AB227086)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BS69 antibody (AB227086)

Paraffin-embedded human colon carcinoma tissue stained for BS69 using ab227086 at 1/250 dilution in immunohistochemical analysis.

Immunocytochemistry/ Immunofluorescence - Anti-BS69 antibody (AB227086)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-BS69 antibody (AB227086)

4% paraformaldehyde-fixed A431 (human epidermoid carcinoma cell line) cells stained for BS69 (green) using ab227086 at 1/500 dilution in ICC/IF.

Blue : Hoechst 33342 staining.

Western blot - Anti-BS69 antibody (AB227086)
  • WB

Supplier Data

Western blot - Anti-BS69 antibody (AB227086)

7.5% SDS-PAGE gel.

All lanes:

Western blot - Anti-BS69 antibody (ab227086) at 1/1000 dilution

Lane 1:

Non-transfected HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) cell lysate

Lane 2:

BS69 transfected HEK-293T cell lysate

Predicted band size: 71 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB, ICC/IF, IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human ZMYND11. The exact immunogen used to generate this antibody is proprietary information.

Q15326

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/100 - 1/1000", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/100 - 1/1000", "ICCIF-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rhesus monkey": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 10% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2) (By similarity). Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Binds non-specifically to dsDNA (PubMed : 24675531). Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth.. (Microbial infection) Inhibits Epstein-Barr virus EBNA2-mediated transcriptional activation and host cell proliferation, through direct interaction.
See full target information ZMYND11
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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

iScience 28:112295 PubMed40264797

2025

Fate plasticity of interneuron specification.

Applications

Unspecified application

Species

Unspecified reactive species

Mohammed A Mostajo-Radji,Walter R Mancia Leon,Arnar Breevoort,Jesus Gonzalez-Ferrer,Hunter E Schweiger,Julian Lehrer,Li Zhou,Matthew T Schmitz,Yonatan Perez,Tanzila Mukhtar,Ash Robbins,Julia Chu,Madeline G Andrews,Frederika N Sullivan,Dario Tejera,Eric C Choy,Mercedes F Paredes,Mircea Teodorescu,Arnold R Kriegstein,Arturo Alvarez-Buylla,Alex A Pollen

Cell stem cell 28:877-893.e9 PubMed33631116

2021

Regional identity of human neural stem cells determines oncogenic responses to histone H3.3 mutants.

Applications

Unspecified application

Species

Unspecified reactive species

Raul Bardini Bressan,Benjamin Southgate,Kirsty M Ferguson,Carla Blin,Vivien Grant,Neza Alfazema,Jimi C Wills,Maria Angeles Marques-Torrejon,Gillian M Morrison,James Ashmore,Faye Robertson,Charles A C Williams,Leanne Bradley,Alex von Kriegsheim,Richard A Anderson,Simon R Tomlinson,Steven M Pollard
View all publications
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