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AB227162

Anti-BTG1 antibody

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(1 Publication)

Rabbit Polyclonal BTG1 antibody. Suitable for IHC-P and reacts with Mouse samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human BTG1.

View Alternative Names

Protein BTG1, B-cell translocation gene 1 protein, BTG1

1 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BTG1 antibody (AB227162)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BTG1 antibody (AB227162)

Paraffin-embedded mouse prostate tissue stained for BTG1 with ab227162 at 1/500 dilution in immunohistochemical analysis.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse

Applications

IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human BTG1. The exact immunogen used to generate this antibody is proprietary information.

P62324

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Mouse": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/100 - 1/1000", "IHCP-species-notes": "<p></p>" }, "Rat": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Chicken": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Cow": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Pig": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rhesus monkey": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Sheep": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: PBS, 20% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

BTG1 also known as B-cell translocation gene 1 protein is a member of the BTG/TOB family. This protein generally serves a role in cell cycle regulation by acting as an antiproliferative agent. BTG1 has an approximate mass of 22 kDa. Its expression is mainly found in the hematopoietic system with notable presence in the lymphoid tissues suggesting a significant role in immune system functionality.
Biological function summary

BTG1 affects fundamental cellular processes through its interaction with other proteins. This protein plays a role in cell cycle regulation by influencing key processes like proliferation differentiation and apoptosis. BTG1 functions as part of a complex that involves interactions with CCR4-NOT transcription complex and various growth regulators. These engagements highlight the multifaceted roles of BTG1 in cell regulation.

Pathways

BTG1 plays an important role in the regulation of cellular growth and differentiation pathways. It interfaces with key players such as cyclin D1 and p53 both important for cell cycle progression and DNA damage response pathways. These interactions position BTG1 within the broader regulatory network of cell cycle control maintaining cellular growth homeostasis and preventing unregulated proliferation.

BTG1 involvement has been observed in certain types of cancer particularly leukemia. Its expression levels can indicate the progression or prognosis of such malignancies. BTG1 often shows altered expression levels in conjunction with proteins like B-cell lymphoma 2 (Bcl-2) in the context of hematological disorders. Understanding BTG1 interactions provides valuable insight into potential therapeutic targets for managing these diseases.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Anti-proliferative protein.
See full target information BTG1
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Journal of dental research 98:1262-1270 PubMed31454276

2019

Axin2-Mesenchymal PDL Cells, Instead of K14 Epithelial Cells, Play a Key Role in Rapid Cementum Growth.

Applications

Unspecified application

Species

Unspecified reactive species

X Xie,J Wang,K Wang,C Li,S Zhang,D Jing,C Xu,X Wang,H Zhao,J Q Feng
View all publications
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Product promise

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