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AB192250

Anti-C10orf57 antibody [EPR14666]

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(1 Publication)

Rabbit Recombinant Monoclonal C10orf57 antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication.

View Alternative Names

C10orf57, TMEM254, Transmembrane protein 254

1 Images
Western blot - Anti-C10orf57 antibody [EPR14666] (AB192250)
  • WB

Supplier Data

Western blot - Anti-C10orf57 antibody [EPR14666] (AB192250)

Blocking/Dilution buffer : 5% NFDM /TBST.

All lanes:

Western blot - Anti-C10orf57 antibody [EPR14666] (ab192250) at 1/1000 dilution

Lane 1:

HepG2 cell lysate at 10 µg

Lane 2:

HeLa cell lysate at 10 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Predicted band size: 14 kDa

false

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR14666

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000", "WB-species-notes": "<p></p>" } } }
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Product details

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

C10orf57 also known as UNQ8419 or HSPC203 is a human protein whose specific mechanical function remains largely undefined. It is approximately 40 kDa in size. Expression of C10orf57 occurs widely across various tissues with noticeable levels in the brain and testis. This ubiquitous presence suggests that C10orf57 may serve a general role in cellular function or structure although detailed insights are currently limited.
Biological function summary

This protein likely plays a significant part in cellular processes potentially through interactions or complex formations though direct evidence for complex involvement is not yet established. Studies have indicated a possible function related to nucleic acid binding or protein-protein interactions. Understanding the detailed biological roles of C10orf57 requires further research to clarify its specific contributions inside the cell.

Pathways

C10orf57 may interact with several cellular pathways yet clear participation in particular pathways like signal transduction or cell cycle regulation has not been confirmed. Current research explores its possible involvement in pathways connected to DNA repair or cellular stress response. Related proteins such as those in the DNA damage response family might show functional interaction with C10orf57 although these links are speculative at this point.

Ongoing studies suggest an association of C10orf57 with neurodevelopmental disorders and cancer. Genetic aberrations in the expression of C10orf57 might contribute to neurological conditions possibly linked to disruptions in brain protein networks. Additionally its altered expression patterns have been observed in certain cancer types which may involve associations with proteins involved in cell proliferation like p53. Future work is essential to unravel the detailed roles of C10orf57 in these diseases fully.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

See full target information TMEM254
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Genome medicine 13:58 PubMed33853662

2021

PRMT1-mediated H4R3me2a recruits SMARCA4 to promote colorectal cancer progression by enhancing EGFR signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Bing Yao,Tao Gui,Xiangwei Zeng,Yexuan Deng,Zhi Wang,Ying Wang,Dongjun Yang,Qixiang Li,Peipei Xu,Ruifeng Hu,Xinyu Li,Bing Chen,Jin Wang,Ke Zen,Haitao Li,Melissa J Davis,Marco J Herold,Hua-Feng Pan,Zhi-Wei Jiang,David C S Huang,Ming Liu,Junyi Ju,Quan Zhao
View all publications
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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