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AB180585

Anti-C16orf45 antibody [EPR14087]

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(1 Publication)

Rabbit Recombinant Monoclonal C16orf45 antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication.

View Alternative Names

C16orf45, BMERB1, bMERB domain-containing protein 1

2 Images
Western blot - Anti-C16orf45 antibody [EPR14087] (AB180585)
  • WB

Supplier Data

Western blot - Anti-C16orf45 antibody [EPR14087] (AB180585)

All lanes:

Western blot - Anti-C16orf45 antibody [EPR14087] (ab180585) at 1/5000 dilution

Lane 1:

Human fetal brain tissue lysate at 10 µg

Lane 2:

Human adrenal gland tissue lysate at 10 µg

Secondary

All lanes:

Anti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1000 dilution

Predicted band size: 24 kDa

false

Western blot - Anti-C16orf45 antibody [EPR14087] (AB180585)
  • WB

Supplier Data

Western blot - Anti-C16orf45 antibody [EPR14087] (AB180585)

All lanes:

Western blot - Anti-C16orf45 antibody [EPR14087] (ab180585) at 1/5000 dilution

All lanes:

A673 cell lysate at 10 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Predicted band size: 24 kDa

false

  • Carrier free

    Anti-C16orf45 antibody [EPR14087] - BSA and Azide free

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR14087

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "<p></p>" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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Product details

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Shipped at conditions
Conditional Ambient
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

C16orf45 is a protein encoded by the C16orf45 gene also known in the scientific community as Chromosome 16 open reading frame 45. The exact mass of this protein remains under investigation but it is generally expressed throughout human tissues with higher expression noted in certain cancerous tissues. Researchers continue to explore its distribution to understand its varied roles in different cellular contexts.
Biological function summary

The C16orf45 protein appears to participate in cellular processes linked to proliferation and differentiation. While exact interactions at the molecular level are not fully mapped some studies suggest its involvement in forming part of a multi-protein complex that may influence these processes. As such it could have broader implications for understanding basic mechanisms controlling cell behavior.

Pathways

Current research has identified some connections between C16orf45 and key cellular signaling pathways such as the MAPK/ERK pathway. This pathway is important in transmitting signals from the cell surface to the DNA within the nucleus affecting cellular activities like division and growth. C16orf45 may interact closely with proteins like ERK helping to modulate the outcomes of this pathway and possibly impacting gene expression modifications.

Altered expression patterns of C16orf45 have been linked to specific cancer types notably breast cancer. The protein appears to interact with oncogenes like HER2 possibly influencing cancer progression or resistance to therapies. Researchers aim to further dissect these relationships as C16orf45 could serve as a potential biomarker or a novel therapeutic target in oncology.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

See full target information BMERB1
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Developmental cell 57:387-397.e4 PubMed35134345

2022

The Lipid Droplet Knowledge Portal: A resource for systematic analyses of lipid droplet biology.

Applications

Unspecified application

Species

Unspecified reactive species

Niklas Mejhert,Katlyn R Gabriel,Scott Frendo-Cumbo,Natalie Krahmer,Jiunn Song,Leena Kuruvilla,Chandramohan Chitraju,Sebastian Boland,Dong-Keun Jang,Marcin von Grotthuss,Maria C Costanzo,Mikael Rydén,James A Olzmann,Jason Flannick,Noël P Burtt,Robert V Farese,Tobias C Walther
View all publications
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com