Anti-C16orf48 antibody

Supplementary info

This supplementary information is collated from multiple sources and compiled automatically.

Activity summary

C16orf48 also known as FLJ20489 is a protein with an approximate molecular mass of 13 kDa. It exhibits higher expression levels in certain tissues including the brain and liver indicating a tissue-specific role. The protein's mechanical function involves RNA binding suggesting its involvement in RNA processing or regulation. The well-defined binding domain aids in precise targeting within the cellular environment reinforcing its regulatory capacities.

Biological function summary

The actions of C16orf48 influence cellular processes particularly in gene expression regulation. C16orf48 participates in a multi-protein complex suggesting its interactions with other macromolecules elevate its functional significance. While not all the protein interactions and functions are thoroughly characterized its ability to bind RNA points towards an important role in post-transcriptional modifications or other RNA-related activities affecting how genes are expressed or silenced in different conditions.

Pathways

C16orf48 is implicated in pathways linked to RNA metabolic processes and gene expression regulation. Evidence shows involvement in the mRNA splicing pathway where it potentially interacts with well-studied splicing factors. The presence of related proteins like U2AF2 or SF3B1 within these pathways suggests that C16orf48 might influence alternative splicing events which can change the protein output from genes and lead to variations in cellular functions.

Associated diseases and disorders

Mutations or dysregulation of C16orf48 have been associated with neurological disorders and liver diseases. In particular aberrant expression of C16orf48 can have implications in conditions such as Alzheimer's disease where connection to proteins like tau or amyloid precursor protein (APP) suggests a regulatory role in their gene expression. Additionally liver disease connections have drawn attention towards C16orf48's potential impact in hepatocyte function making it an important target for further research in understanding complex disease mechanisms.