JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB249981

Anti-C16orf88 antibody [EPR12561] - BSA and Azide free

Be the first to review this product! Submit a review

|

(1 Publication)

Rabbit Recombinant Monoclonal C16orf88 antibody. Carrier free. Suitable for IP, WB and reacts with Human samples. Cited in 1 publication.

View Alternative Names

C16orf88, FAM191A, TSG118, KNOP1, Lysine-rich nucleolar protein 1, Protein FAM191A, Testis-specific gene 118 protein

2 Images
Western blot - Anti-C16orf88 antibody [EPR12561] - BSA and Azide free (AB249981)
  • WB

Supplier Data

Western blot - Anti-C16orf88 antibody [EPR12561] - BSA and Azide free (AB249981)

This data was developed using ab177476, the same antibody clone in a different buffer formulation.

All lanes:

Western blot - Anti-C16orf88 antibody [EPR12561] (<a href='/en-us/products/primary-antibodies/c16orf88-antibody-epr12561-ab177476'>ab177476</a>) at 1/1000 dilution

Lane 1:

Human testis lysate at 10 µg

Lane 2:

Human seminoma lysate at 10 µg

Secondary

All lanes:

HRP labelled goat anti-rabbit at 1/2000 dilution

Predicted band size: 52 kDa

false

Immunoprecipitation - Anti-C16orf88 antibody [EPR12561] - BSA and Azide free (AB249981)
  • IP

Supplier Data

Immunoprecipitation - Anti-C16orf88 antibody [EPR12561] - BSA and Azide free (AB249981)

This data was developed using ab177476, the same antibody clone in a different buffer formulation.

Immunoprecipitation of C16orf88 from Human testis lysate using ab177476 at 1/10 or 1X PBS (negative control) (lane 2), and HRP-conjugated anti-rabbit IgG preferentially detecting the non-reduced form of rabbit IgG.

All lanes:

Immunoprecipitation - Anti-C16orf88 antibody [EPR12561] (<a href='/en-us/products/primary-antibodies/c16orf88-antibody-epr12561-ab177476'>ab177476</a>)

Predicted band size: 52 kDa

false

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR12561

Isotype

IgG

Carrier free

Yes

Reacts with

Human

Applications

WB, IP

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "testedAndGuaranteed", "IP-species-dilution-info": "", "IP-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>" } } }
style
left-column

Product details

ab249981 is the carrier-free version of ab177476.

Species reactivity
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species.
Please contact us for more information.

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.

Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

Compatibility
This product is compatible with the Maxpar® Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar® is a trademark of Fluidigm Canada Inc.

style
left-column

Properties and storage information

Form
Liquid
Purification technique
Affinity purification
Storage buffer
pH: 7.2 - 7.4 Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Do Not Freeze
style
left-column

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

C16orf88 also known as Chromosome 16 Open Reading Frame 88 is an uncharacterized protein that plays a role at the cellular level. With a molecular mass of approximately 44 kDa C16orf88 is expressed in various tissues with substantial expression in the brain and testis. Its exact functions are not fully understood but research suggests it may participate in cellular structural frameworks or signaling pathways due to its presence across different cell types.
Biological function summary

The protein influences cellular processes by contributing to the regulation of cell cycle or structural integrity. Current studies indicate that C16orf88 might form part of a multiprotein complex which supports its role in maintaining cellular organization or facilitating communication between signaling molecules. Although information remains limited C16orf88's expression pattern suggests it may affect cellular differentiation and developmental biology particularly in neural tissues.

Pathways

Existing evidence connects C16orf88 to neurological and reproductive pathways. It may join key components of MAPK/ERK signaling pathways and demonstrate interactions with proteins such as ERK1/2 which are known regulators of cell division and differentiation. Participation in these pathways positions C16orf88 as a contributor to signal transduction that affects overall physiological responses and developmental processes.

C16orf88 shows potential linkage with neurodegenerative diseases and reproductive health issues. Disruption in its function or expression has associations with conditions like Alzheimer's disease where proteins such as TAU related to C16orf88 play a central role in disease progression. Similarly abnormal activity can trigger reproductive disorders by affecting related proteins involved in testicular function though precise mechanisms and pathways require further research for clarity.
style
left-column
style
left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

Target data

See full target information KNOP1
style
left-column

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Cell death discovery 7:357 PubMed34785642

2021

UBE2S promotes cell chemoresistance through PTEN-AKT signaling in hepatocellular carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Liang Gui,Sicai Zhang,Yongzi Xu,Hongwei Zhang,Ying Zhu,Lianbao Kong
View all publications
style
left-column
style
left-column
style
right-column

Complementary Products

Primary Antibodies

AB153904

Anti-HOXC10 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HOXC10 antibody (AB153904)

  • 5
  • 2
Primary Antibodies

AB126356

Anti-WWC2 antibody

Immunocytochemistry/ Immunofluorescence - Anti-WWC2 antibody (AB126356)

  • 0
  • 0
Primary Antibodies

AB184774

Anti-PAIP2B antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PAIP2B antibody (AB184774)

  • 0
  • 0
Primary Antibodies

AB223477

Anti-ZKSCAN3 antibody

Immunocytochemistry/ Immunofluorescence - Anti-ZKSCAN3 antibody (AB223477)

  • 0
  • 0

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com