Anti-C17orf57 antibody

Supplementary info

This supplementary information is collated from multiple sources and compiled automatically.

Activity summary

C17orf57 also known as GCP2 or GC-rich promoter binding protein 2 is a 17 kDa protein. It has a role in transcriptional regulation processes. This protein is ubiquitously expressed with higher levels in tissues such as the brain and skeletal muscle. It connects to RNA processing and possibly interacts with various components of the transcription machinery.

Biological function summary

C17orf57 contributes to complex processes involved in the regulation of gene expression. It interacts with some components of RNA polymerase II. This interaction suggests that C17orf57 might assist in modulating the synthesis of RNA transcripts a critical step in the flow of genetic information from DNA to protein. This protein may also play a part in nuclear processes related to mRNA stability and localization.

Pathways

C17orf57 plays a significant role in transcription regulation and RNA processing pathways. It works alongside components in the DNA-dependent transcription pathway where interactions with RNA polymerase II are relevant. Additionally C17orf57's presence in an mRNA processing pathway suggests its involvement with proteins like GRWD1 which are associated with gene expression and regulatory events.

Associated diseases and disorders

C17orf57 has some association with cancer and neurodegenerative diseases. Studies show that its dysregulation may impact cellular processes leading to abnormal cell proliferation and possibly contributing to oncogenesis. C17orf57's interactions with proteins like CTCF may influence chromatin architecture which can impact regulatory pathways involved in these diseases. Alterations in its expression or function might also influence conditions affecting nervous system health.