Rabbit Polyclonal C18orf25 antibody. Suitable for WB, IHC-P and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human C18orf25 aa 1 to C-terminus.
IgG
Rabbit
pH: 7
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 79.99% PBS, 20% Glycerol (glycerin, glycerine)
Liquid
Polyclonal
WB | IHC-P | |
---|---|---|
Human | Tested | Tested |
Species | Dilution info | Notes |
---|---|---|
Species Human | Dilution info 1/500.00000 - 1/3000.00000 | Notes - |
Species | Dilution info | Notes |
---|---|---|
Species Human | Dilution info 1/100.00000 - 1/1000.00000 | Notes - |
AMPK substrate important for exercise capacity and skeletal muscle function. Required for normal contraction-induced signaling.(Microbial infection) Upon Epstein-Barr virus (EBV) infection, suppresses viral BZLF1 expression and subsequent EBV reactivation by interacting with JUN and inhibiting its transcriptional activitor activity on BZLF1 Z promoter.
ARKL1, C18orf25, ARK2N, ARKL1, C18orf25, Protein ARK2N, ARKadia-like protein 1, Arkadia (RNF111) N-terminal like PKA signaling regulator protein 2N
Rabbit Polyclonal C18orf25 antibody. Suitable for WB, IHC-P and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human C18orf25 aa 1 to C-terminus.
IgG
Rabbit
pH: 7
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 79.99% PBS, 20% Glycerol (glycerin, glycerine)
Liquid
Polyclonal
Affinity purification Immunogen
Blue Ice
+4°C
-20°C
Upon delivery aliquot
Avoid freeze / thaw cycle
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This supplementary information is collated from multiple sources and compiled automatically.
C18orf25 also known as Chromosome 18 Open Reading Frame 25 is a protein with a molecular mass of about 13 kDa. This protein serves mechanical roles associated with intracellular signaling although its precise functions remain under research. Studies show expression of C18orf25 in various tissues with notably higher levels in cardiac and skeletal muscle tissues. The widespread expression suggests a role in multiple cellular processes.
This protein acts as part of a signaling network influencing cellular responses. While C18orf25 does not form part of a major protein complex it interacts with other cellular components to maintain homeostasis. It may regulate processes linked to muscle function and energy metabolism. Through these interactions it might play a role in maintaining cellular architecture.
C18orf25's function plays into metabolic and muscle maintenance pathways. It is linked to the energy production pathway and possibly supports mitochondrial function. C18orf25 interacts indirectly with proteins like AKT as part of the signal transduction cascades which regulate cell growth and survival. These connections suggest that C18orf25 could influence cellular energy balance mechanisms.
Research links C18orf25 with metabolic syndrome and cardiomyopathy. This connection comes from its role in energy regulation and muscle tissue function suggesting dysfunction in these areas can contribute to these diseases. The protein's interaction with factors like AMPK implies that imbalances in these pathways could affect disease progression. Understanding C18orf25 could illuminate aspects of these conditions bringing potential for therapeutic targeting.
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10% SDS PAGE
All lanes: Western blot - Anti-C18orf25 antibody (ab151616) at 1/1000 dilution
Lane 1: HeLa whole cell lysate at 30 µg
Lane 2: HepG2 whole cell lysate at 30 µg
Predicted band size: 43 kDa
Immunohistochemical analysis of paraffin-embedded Human HeLa xenograft tissue labeling C18orf25 with ab151616 at 1/500 dilution.
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