Rabbit Polyclonal C18orf32 antibody. Suitable for IHC-P, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human C18orf32 aa 1 to C-terminus.
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Publications
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- Developmental cell 44:97-112.e72017A Proximity Labeling Strategy Provides Insights into the Composition and Dynamics of Lipid Droplet Proteomes.Applications:Unspecified applicationReactive species:Unspecified reactive speciesKirill Bersuker,Clark W H Peterson,Milton To,Steffen J Sahl,Victoria Savikhin,Elizabeth A Grossman,Daniel K Nomura,James A OlzmannPubMed 29275994
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine)- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- Recombinant Fragment Protein within Human C18orf32 aa 1 to C-terminus. The exact immunogen used to generate this antibody is proprietary information. Database link Q8TCD1
Reactivity data
Select an application| IHC-P | ICC/IF | |
|---|---|---|
| Human | Tested | Tested |
IHC-P
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/20.00000 - 1/50.00000 | Notes Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
ICC/IF
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 0.25000-2.00000 µg/mL | Notes - |
Target data
Function
May activate the NF-kappa-B signaling pathway.
Alternative names
UPF0729 protein C18orf32, Putative NF-kappa-B-activating protein 200, C18orf32
Recommended products
Rabbit Polyclonal C18orf32 antibody. Suitable for IHC-P, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human C18orf32 aa 1 to C-terminus.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine)- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- Recombinant Fragment Protein within Human C18orf32 aa 1 to C-terminus. The exact immunogen used to generate this antibody is proprietary information. Database link Q8TCD1
- Purification technique
- Affinity purification Immunogen
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Notes
Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.
If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.
Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.
Supplementary info
- This supplementary information is collated from multiple sources and compiled automatically.
- Activity summary
C18orf32 also known as Chromosome 18 Open Reading Frame 32 is a protein-coding gene with limited characterization. It has a predicted mass of approximately 25 kDa and it expresses mainly in tissues such as the skeletal muscle heart and brain. The protein plays roles in cellular processes that scientists are still mapping in detail. Its expression levels and patterns suggest it may participate in specialized functions in specific tissues.
- Biological function summary
C18orf32 appears to influence cellular functions linked to muscle and nerve physiology. It does not currently link to any specific protein complexes so the exact biological mechanisms remain under investigation. Researchers hypothesize that its role might include modulation of cellular responses or support of specific mitochondrial processes in myocytes or neurons due to its expression pattern.
- Pathways
C18orf32 interacts within cellular frameworks that impact energy metabolism and neural communication. It potentially associates with pathways like ATP production or synaptic transmission processes although detailed maps of these pathways remain incomplete. Related proteins such as ATP synthase or synaptophysin could provide indirect interactions but more research needs to establish these connections definitively.
- Associated diseases and disorders
C18orf32 has associations with conditions affecting muscle or brain tissues like muscular dystrophy and neurodegenerative diseases. Mutations or malfunctions in this protein might link to disrupted energy management in muscle cells or synaptic dysfunctions in neurons possibly interacting with proteins such as dystrophin in muscular dystrophy or tau in neurodegenerative conditions. Further investigations aim to clarify C18orf32's implications in these diseases.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
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5 product images
Immunocytochemistry/ Immunofluorescence - Anti-C18orf32 antibody (ab122677)
Immunofluorescent staining of Human cell line U-2 OS shows positivity in vesicles. Recommended concentration of ab122677 1-4 µg/ml. Cells treated with PFA/Triton X-100.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C18orf32 antibody (ab122677)
Immunohistochemical analysis of formalin-fixed, paraffin-embedded human cerebral cortex tissue labeling C18orf32 with ab122677 at 1/50.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C18orf32 antibody (ab122677)
Immunohistochemical analysis of formalin-fixed, paraffin-embedded human kidney tissue labeling C18orf32 with ab122677 at 1/50.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C18orf32 antibody (ab122677)
Immunohistochemical analysis of formalin-fixed, paraffin-embedded human duodenum tissue labeling C18orf32 with ab122677 at 1/50.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C18orf32 antibody (ab122677)
Immunohistochemical analysis of formalin-fixed, paraffin-embedded human skeletal muscle tissue labeling C18orf32 with ab122677 at 1/50.
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