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AB122677

Anti-C18orf32 antibody

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(1 Publication)

Rabbit Polyclonal C18orf32 antibody. Suitable for IHC-P, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human C18orf32 aa 1 to C-terminus.

View Alternative Names

UPF0729 protein C18orf32, Putative NF-kappa-B-activating protein 200, C18orf32

5 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C18orf32 antibody (AB122677)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C18orf32 antibody (AB122677)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human duodenum tissue labeling C18orf32 with ab122677 at 1/50.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C18orf32 antibody (AB122677)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C18orf32 antibody (AB122677)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human cerebral cortex tissue labeling C18orf32 with ab122677 at 1/50.

Immunocytochemistry/ Immunofluorescence - Anti-C18orf32 antibody (AB122677)
  • ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-C18orf32 antibody (AB122677)

Immunofluorescent staining of Human cell line U-2 OS shows positivity in vesicles. Recommended concentration of ab122677 1-4 µg/ml. Cells treated with PFA/Triton X-100.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C18orf32 antibody (AB122677)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C18orf32 antibody (AB122677)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human skeletal muscle tissue labeling C18orf32 with ab122677 at 1/50.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C18orf32 antibody (AB122677)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C18orf32 antibody (AB122677)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded human kidney tissue labeling C18orf32 with ab122677 at 1/50.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

ICC/IF, IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human C18orf32 aa 1 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q8TCD1

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/50", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "0.25-2 µg/mL", "ICCIF-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

C18orf32 also known as Chromosome 18 Open Reading Frame 32 is a protein-coding gene with limited characterization. It has a predicted mass of approximately 25 kDa and it expresses mainly in tissues such as the skeletal muscle heart and brain. The protein plays roles in cellular processes that scientists are still mapping in detail. Its expression levels and patterns suggest it may participate in specialized functions in specific tissues.
Biological function summary

C18orf32 appears to influence cellular functions linked to muscle and nerve physiology. It does not currently link to any specific protein complexes so the exact biological mechanisms remain under investigation. Researchers hypothesize that its role might include modulation of cellular responses or support of specific mitochondrial processes in myocytes or neurons due to its expression pattern.

Pathways

C18orf32 interacts within cellular frameworks that impact energy metabolism and neural communication. It potentially associates with pathways like ATP production or synaptic transmission processes although detailed maps of these pathways remain incomplete. Related proteins such as ATP synthase or synaptophysin could provide indirect interactions but more research needs to establish these connections definitively.

C18orf32 has associations with conditions affecting muscle or brain tissues like muscular dystrophy and neurodegenerative diseases. Mutations or malfunctions in this protein might link to disrupted energy management in muscle cells or synaptic dysfunctions in neurons possibly interacting with proteins such as dystrophin in muscular dystrophy or tau in neurodegenerative conditions. Further investigations aim to clarify C18orf32's implications in these diseases.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

May activate the NF-kappa-B signaling pathway.
See full target information C18orf32
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Developmental cell 44:97-112.e7 PubMed29275994

2017

A Proximity Labeling Strategy Provides Insights into the Composition and Dynamics of Lipid Droplet Proteomes.

Applications

Unspecified application

Species

Unspecified reactive species

Kirill Bersuker,Clark W H Peterson,Milton To,Steffen J Sahl,Victoria Savikhin,Elizabeth A Grossman,Daniel K Nomura,James A Olzmann
View all publications
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Product promise

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For full details, please see our Terms & Conditions

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