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AB236288

Anti-C19orf47 antibody

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(1 Publication)

Rabbit Polyclonal C19orf47 antibody. Suitable for WB, IHC-P and reacts with Mouse, Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human C19orf47 aa 1-300.

View Alternative Names

Uncharacterized protein C19orf47, C19orf47

3 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C19orf47 antibody (AB236288)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C19orf47 antibody (AB236288)

Paraffin-embedded human testis tissue stained for C19orf47 using ab236288 at 1/100 dilution in immunohistochemical analysis.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C19orf47 antibody (AB236288)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C19orf47 antibody (AB236288)

Paraffin-embedded human small intestine tissue stained for C19orf47 using ab236288 at 1/100 dilution in immunohistochemical analysis.

Western blot - Anti-C19orf47 antibody (AB236288)
  • WB

Supplier Data

Western blot - Anti-C19orf47 antibody (AB236288)

All lanes:

Western blot - Anti-C19orf47 antibody (ab236288) at 1/500 dilution

All lanes:

Mouse muscle lysate

Secondary

All lanes:

Goat polyclonal to rabbit IgG at 1/10000 dilution

Predicted band size: 45 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse, Human

Applications

IHC-P, WB

applications

Immunogen

Recombinant Fragment Protein within Human C19orf47 aa 1-300. The exact immunogen used to generate this antibody is proprietary information.

Q8N9M1

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/200", "IHCP-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/2000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein G
Purification notes
Purity >95%.
Storage buffer
pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

C19orf47 also known by alternate names such as Chromosome 19 Open Reading Frame 47 is a protein-coding gene located on human chromosome 19. It encodes a protein with a mass of approximately 46 kDa. This protein has localization in the cytoplasm and nucleus showing expression across various tissues but particularly enriched in immune cells. Researchers have suggested roles in cellular processes due to its conserved domains but the exact mechanical functions of C19orf47 remain not fully described.
Biological function summary

C19orf47 plays a role in the regulation of immune response possibly impacting cell signaling and proliferation. It functions as part of a larger protein complex interacting with key cellular machinery to modulate various biological processes. The protein has close associations with other regulatory proteins that influence immune cell dynamics. This suggests that C19orf47 may have broader implications in immune system homeostasis and adaptability.

Pathways

The evolutionarily conserved protein C19orf47 is involved in pathways linked to immune signaling networks. It participates in the regulation of signal transduction pathways such as the NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) pathway critical for immune and inflammatory responses. Additionally C19orf47 interacts with proteins like IκB influencing the pathway's activation and inhibition processes. This indicates its potential role in modulating immune responses and cellular defense mechanisms.

Research implicates C19orf47 in conditions related to immune dysregulation such as autoimmune diseases and certain cancers. It has connections to proteins involved in autoimmune diseases highlighting a potential role in disease pathogenesis due to alterations in immune signaling. Investigations continue to explore its association with other proteins like TNF (tumor necrosis factor) in these disorders. Understanding the involvement of C19orf47 in disease can lead to new insights into disease mechanisms and therapeutic targets.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

See full target information C19orf47
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Communications biology 8:514 PubMed40155473

2025

Defining gastric cancer ecology: the crucial roles of TREM2 macrophages and fibroblasts in tumor microenvironments.

Applications

Unspecified application

Species

Unspecified reactive species

Qianqian Cao,Dianshui Sun,Can Tu,Jihua Wang,Runjia Fu,Rumei Gong,Yueying Xiao,Qin Liu,Xiaomei Li
View all publications
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Product promise

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