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Anti-C1q antibody [C1QA/2956] (ab268120) is a mouse monoclonal antibody that is used to detect C1q in IHC-P. Suitable for Human samples.


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Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C1q antibody [C1QA/2956] (AB268120), expandable thumbnail
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C1q antibody [C1QA/2956] (AB268120), expandable thumbnail
  • Protein Array - Anti-C1q antibody [C1QA/2956] (AB268120), expandable thumbnail

Publications

Key facts

Isotype
IgG2b
Host species
Mouse
Storage buffer

pH: 7.2 - 7.4
Preservative: 0.05% Sodium azide
Constituents: PBS, 0.05% BSA

Form
Liquid
Clonality
Monoclonal

Immunogen

  • Recombinant Fragment Protein within Human C1QA aa 100 to C-terminus. The exact immunogen used to generate this antibody is proprietary information. Database link P02745

Reactivity data

Select an application
Product promiseTestedExpectedPredictedNot recommended
Protein ArrayIHC-P
Human
Tested
Tested

Tested
Tested

Species
Human
Dilution info
-
Notes

Perform heat-mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

Tested
Tested

Species
Human
Dilution info
1-2 µg/mL
Notes

Perform heat-mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

Associated Products

Select an associated product type

1 product for Alternative Version

4 products for Alternative Product

Target data

Function

C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.

Alternative names

Recommended products

Anti-C1q antibody [C1QA/2956] (ab268120) is a mouse monoclonal antibody that is used to detect C1q in IHC-P. Suitable for Human samples.


Key facts

Isotype
IgG2b
Form
Liquid
Clonality
Monoclonal
Immunogen
  • Recombinant Fragment Protein within Human C1QA aa 100 to C-terminus. The exact immunogen used to generate this antibody is proprietary information. Database link P02745
Clone number
C1QA/2956
Purification technique
Affinity purification Protein A/G
Light chain type
kappa
Concentration
Loading...
Purification notes

Purified from bioreactor concentrate.

Storage

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Notes

What is this antibody validated in?


Anti-C1q antibody [C1QA/2956] (ab268120) is a mouse monoclonal antibody and is validated for use in Immunohistochemistry (IHC-P) in Human samples.

Other related products


We have a range of other formats of antibody clone [C1QA/2956] also available for your convenience:
ab268120, Carrier free - Anti-C1q antibody [C1QA/2956] - BSA and Azide free ab268243



Product promise

We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.

In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
Terms & Conditions.

3 product images

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C1q antibody [C1QA/2956] (ab268120), expandable thumbnail

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C1q antibody [C1QA/2956] (ab268120)

    Formalin-fixed, paraffin-embedded human liver tissue stained for C1q using ab268120 at 2 μg/ml in immunohistochemical analysis.

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C1q antibody [C1QA/2956] (ab268120), expandable thumbnail

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C1q antibody [C1QA/2956] (ab268120)

    Formalin-fixed, paraffin-embedded human kidney tissue stained for C1q using ab268120 at 2 μg/ml in immunohistochemical analysis.

  • Protein Array - Anti-C1q antibody [C1QA/2956] (ab268120), expandable thumbnail

    Protein Array - Anti-C1q antibody [C1QA/2956] (ab268120)

    Protein Array containing more than 19,000 full-length human proteins using ab268120.

    Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Downloads

Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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