Anti-C1q antibody [JL-1] (ab71940) is a mouse monoclonal antibody detecting C1q in ELISA, Dot Blot. Suitable for Human, Mouse.
- Over 30 publications
- Trusted since 2010
Images
![Dot Blot - Anti-C1q antibody [JL-1] (AB71940), expandable thumbnail](https://content.abcam.com/products/images/c1q-antibody-jl-1-ab71940--dot-blot-img8831.jpg/_jcr_content/renditions/webp-475.webp "Dot Blot - Anti-C1q antibody [JL-1] (AB71940)")
![ELISA - Anti-C1q antibody [JL-1] (AB71940), expandable thumbnail](https://content.abcam.com/products/images/c1q-antibody-jl-1-ab71940--elisa-img47980.jpg/_jcr_content/renditions/webp-475.webp "ELISA - Anti-C1q antibody [JL-1] (AB71940)")
Publications
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- Journal of neuroinflammation 20:2012023Mesenchymal-derived extracellular vesicles enhance microglia-mediated synapse remodeling after cortical injury in aging Rhesus monkeys.Applications:Unspecified applicationReactive species:Unspecified reactive speciesYuxin Zhou,Hrishti Bhatt,Chromewell A Mojica,Hongqi Xin,Monica A Pessina,Douglas L Rosene,Tara L Moore,Maria MedallaPubMed 37660145
- Investigative ophthalmology & visual science 64:32023Pharmacokinetic and Target Engagement Measures of ANX007, an Anti-C1q Antibody Fragment, Following Intravitreal Administration in Nonhuman Primates.Applications:Unspecified applicationReactive species:Unspecified reactive speciesAnita Grover,Sethu Sankaranarayanan,Vidhu Mathur,Poojan Suri,Haiyan Qiu,Yaisa Andrews-Zwilling,Kirsten Mease,Lori K Taylor,Ellen Cahir-McFarland,Sanjay Keswani,Ted YednockPubMed 36729444
- Frontiers in immunology 13:9194442022Role of complement C1q/C3-CR3 signaling in brain injury after experimental intracerebral hemorrhage and the effect of minocycline treatment.Applications:Unspecified applicationReactive species:Unspecified reactive speciesYonghe Zheng,Linfeng Fan,Siqi Xia,Qiguo Yang,Zhihua Zhang,Huaijun Chen,Hanhai Zeng,Xiongjie Fu,Yucong Peng,Chaoran Xu,Kaibo Yu,Fuyi Liu,Shenglong CaoPubMed 36189326
- Frontiers in nutrition 9:8873782022Efficacy of a vegetal mixture composed of , , and in a mouse model of neuroinflammation: and analysis.Applications:Unspecified applicationReactive species:Unspecified reactive speciesLaura Micheli,Alessandra Toti,Elena Lucarini,Valentina Ferrara,Clara Ciampi,Guendalina Olivero,Anna Pittaluga,Luisa Mattoli,Caroline Pelucchini,Michela Burico,Jacopo Lucci,Donatello Carrino,Alessandra Pacini,Stefano Pallanti,Lorenzo Di Cesare Mannelli,Carla GhelardiniPubMed 36118773
- Molecular microbiology 117:1479-14922022Streptococcus pneumoniae binds collagens and C1q via the SSURE repeats of the PfbB adhesin.Applications:Unspecified applicationReactive species:Unspecified reactive speciesGiuseppe Valerio De Gaetano,Francesco Coppolino,Germana Lentini,Agata Famà,Chiara Cullotta,Ivana Raffaele,Chiara Motta,Giuseppe Teti,Pietro Speziale,Giampiero Pietrocola,Concetta BeninatiPubMed 35570359
- FASEB journal : official publication of the Federation of American Societies for Experimental Biology 36:e223432022URMC-099 prophylaxis prevents hippocampal vascular vulnerability and synaptic damage in an orthopedic model of delirium superimposed on dementia.Applications:Unspecified applicationReactive species:Unspecified reactive speciesPatrick Miller-Rhodes,Herman Li,Ravikanth Velagapudi,Wesley Chiang,Niccolò Terrando,Harris A GelbardPubMed 35535564
- Neurobiology of sleep and circadian rhythms 12:1000732022Microglia are involved in the protection of memories formed during sleep deprivation.Applications:Unspecified applicationReactive species:Unspecified reactive speciesNicholas W Gentry,Thomas McMahon,Maya Yamazaki,John Webb,Thomas D Arnold,Susanna Rosi,Louis J Ptáček,Ying-Hui FuPubMed 35028489
- Bioactive materials 9:183-1972021Engineered neutrophil apoptotic bodies ameliorate myocardial infarction by promoting macrophage efferocytosis and inflammation resolution.Applications:Unspecified applicationReactive species:Unspecified reactive speciesLili Bao,Geng Dou,Ran Tian,Yajie Lv,Feng Ding,Siying Liu,Ruifeng Zhao,Lu Zhao,Jun Zhou,Lin Weng,Yan Dong,Bei Li,Shiyu Liu,Xin Chen,Yan JinPubMed 34820565
- Journal of inflammation research 14:5919-59372021Melatonin Ameliorates Axonal Hypomyelination of Periventricular White Matter by Transforming A1 to A2 Astrocyte via JAK2/STAT3 Pathway in Septic Neonatal Rats.Applications:Unspecified applicationReactive species:Unspecified reactive speciesShuqi Jiang,Huifang Wang,Qiuping Zhou,Qian Li,Nan Liu,Zhenggong Li,Chunbo Chen,Yiyu DengPubMed 34803390
- Science advances 7:eabj34002021Social isolation-related depression accelerates ethanol intake via microglia-derived neuroinflammation.Applications:Unspecified applicationReactive species:Unspecified reactive speciesJin-Seok Lee,Sung-Bae Lee,Dong-Woon Kim,Nara Shin,Seon-Ju Jeong,Chae-Ha Yang,Chang-Gue SonPubMed 34739315
Key facts
- Isotype
- IgG2b
- Host species
- Mouse
- Storage buffer
Constituents: PBS, 0.1% BSA
- Form
- Liquid
- Clonality
- Monoclonal
Immunogen
- Native Full Length Protein corresponding to Mouse C1qa. Database link P98086
Reactivity data
Select an application| ELISA | Dot | |
|---|---|---|
| Human | Expected | Tested |
| Mouse | Expected | Tested |
| Rat | Predicted | Predicted |
| Recombinant full length protein - Mouse | Tested | Not recommended |
ELISA
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Recombinant full length protein - Mouse | Dilution info - | Notes - |
ExpectedExpected
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse, Human | Dilution info Use at an assay dependent concentration. | Notes - |
PredictedPredicted
| Species | Dilution info | Notes |
|---|---|---|
Species Rat | Dilution info - | Notes - |
Dot
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse, Human | Dilution info - | Notes - |
PredictedPredicted
| Species | Dilution info | Notes |
|---|---|---|
Species Rat | Dilution info - | Notes - |
Not recommendedNot recommended
| Species | Dilution info | Notes |
|---|---|---|
Species Recombinant full length protein - Mouse | Dilution info - | Notes - |
Associated Products
Select an associated product type
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Target data
Function
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
Alternative names
Complement C1q subcomponent subunit A, C1QA
Recommended products
Anti-C1q antibody [JL-1] (ab71940) is a mouse monoclonal antibody detecting C1q in ELISA, Dot Blot. Suitable for Human, Mouse.
- Over 30 publications
- Trusted since 2010
Key facts
- Isotype
- IgG2b
- Host species
- Mouse
- Storage buffer
Constituents: PBS, 0.1% BSA
- Form
- Liquid
- Clonality
- Monoclonal
- Immunogen
- Native Full Length Protein corresponding to Mouse C1qa. Database link P98086
- Clone number
- JL-1
- Purification technique
- Affinity purification Protein G
- Epitope
- The monoclonal antibody JL-1is reactive with the collagen-like region (CLR).
- Concentration
- Purification notes
0.2µm filtered.
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Notes
Anti-C1q antibody [JL-1] (ab71940) is a mouse monoclonal antibody and is validated for use in ELISA, Dot Blot in Human, Mouse samples.
Trusted by the scientific community
Anti-C1q [JL-1] (ab71940) was first used in a scientific publication in 2010 and has been cited over 30 times in peer-reviewed journals.
Reviewed by scientists
Anti-C1q [JL-1] (ab71940) has over 10 independent reviews from customers.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
2 product images
![Dot Blot - Anti-C1q antibody [JL-1] (ab71940), expandable thumbnail](https://content.abcam.com/products/images/c1q-antibody-jl-1-ab71940--dot-blot-img8831.jpg "Dot Blot - Anti-C1q antibody [JL-1] (ab71940)")
Dot Blot - Anti-C1q antibody [JL-1] (ab71940)
Dot blot with ab71940 with mouse serum and human plasma with different amounts of C1q.
![ELISA - Anti-C1q antibody [JL-1] (ab71940), expandable thumbnail](https://content.abcam.com/products/images/c1q-antibody-jl-1-ab71940--elisa-img47980.jpg "ELISA - Anti-C1q antibody [JL-1] (ab71940)")
ELISA - Anti-C1q antibody [JL-1] (ab71940)
ab71940 was used as a detection antibody in different concentrations.
Downloads
Product protocols
- Visit the general protocols
- Visit troubleshooting
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