Rabbit Recombinant Monoclonal C1r antibody. Suitable for IP, WB and reacts with Human samples. Cited in 2 publications.
Images
![Western blot - Anti-C1r antibody [EPR14915] (AB185212), expandable thumbnail](https://content.abcam.com/products/images/c1r-antibody-epr14915-ab185212--western-blot-img84940.jpg/_jcr_content/renditions/webp-475.webp "Western blot - Anti-C1r antibody [EPR14915] (AB185212)")
![Immunoprecipitation - Anti-C1r antibody [EPR14915] (AB185212), expandable thumbnail](https://content.abcam.com/products/images/c1r-antibody-epr14915-ab185212--immunoprecipitation-img103522.jpg/_jcr_content/renditions/webp-475.webp "Immunoprecipitation - Anti-C1r antibody [EPR14915] (AB185212)")
Publications
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- Frontiers in immunology 14:11574212023Degradation of collagen I by activated C1s in periodontal Ehlers-Danlos Syndrome.Applications:Unspecified applicationReactive species:Unspecified reactive speciesAlbert Amberger,Johanna Pertoll,Pia Traunfellner,Ines Kapferer-Seebacher,Heribert Stoiber,Lars Klimaschewski,Nicole Thielens,Christine Gaboriaud,Johannes ZschockePubMed 36960056
- Frontiers in immunology 10:25372019Mutations Trigger Constitutive Complement 1 Activation in Periodontal Ehlers-Danlos Syndrome.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.2 - 7.4
Preservative: 0.01% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA- Form
- Liquid
- Clonality
- Monoclonal
Immunogen
- The exact immunogen used to generate this antibody is proprietary information.
Reactivity data
Select an application| IP | WB | |
|---|---|---|
| Human | Tested | Tested |
IP
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/40 - 1/60 | Notes - |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/1000 - 1/10000 | Notes This antibody may be used diluted 1:2000 (PMID: 31749804). |
Associated Products
Select an associated product type
2 products for Alternative Product
Target data
Function
C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system.
Alternative names
Complement C1r subcomponent, Complement component 1 subcomponent r, C1R
Recommended products
Rabbit Recombinant Monoclonal C1r antibody. Suitable for IP, WB and reacts with Human samples. Cited in 2 publications.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.2 - 7.4
Preservative: 0.01% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA- Form
- Liquid
- Clonality
- Monoclonal
- Immunogen
- The exact immunogen used to generate this antibody is proprietary information.
- Clone number
- EPR14915
- Purification technique
- Affinity purification Protein A
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Notes
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free batch production
For more information, read more on recombinant antibodies.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
2 product images
![Western blot - Anti-C1r antibody [EPR14915] (ab185212), expandable thumbnail](https://content.abcam.com/products/images/c1r-antibody-epr14915-ab185212--western-blot-img84940.jpg "Western blot - Anti-C1r antibody [EPR14915] (ab185212)")
Western blot - Anti-C1r antibody [EPR14915] (ab185212)
All lanes: Western blot - Anti-C1r antibody [EPR14915] (ab185212) at 1/5000 dilution
All lanes: Human plasma lysate at 20 µg
SecondaryAll lanes: Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution
Predicted band size: 80 kDa
![Immunoprecipitation - Anti-C1r antibody [EPR14915] (ab185212), expandable thumbnail](https://content.abcam.com/products/images/c1r-antibody-epr14915-ab185212--immunoprecipitation-img103522.jpg "Immunoprecipitation - Anti-C1r antibody [EPR14915] (ab185212)")
Immunoprecipitation - Anti-C1r antibody [EPR14915] (ab185212)
Western blot analysis of immunoprecipitation pellet from Human plasma lysate immunoprecipitated using ab185212 at 1/50 dilution (lane 1) or PBS control (lane 2).
Secondary: Anti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1500 dilution.All lanes: Immunoprecipitation - Anti-C1r antibody [EPR14915] (ab185212)
Predicted band size: 80 kDa
Downloads
Product protocols
- Visit the general protocols
- Visit troubleshooting
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