AB87986

Anti-C1s antibody

Be the first to review this product! Submit a review

(1 Publication)

Rabbit Polyclonal C1S antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication.

View Alternative Names

Complement C1s subcomponent, C1 esterase, Complement component 1 subcomponent s, C1S

1 Images

Unknown

Western blot - Anti-C1s antibody (AB87986)

The Complement C1s subcomponent protein contains a number of potential glycosylation sites (SwissProt) which may explain its migration at a higher molecular weight than predicted. Abcam welcomes customer feedback and would appreciate any comments regarding this product and the data presented above.

All lanes:

Western blot - Anti-C1s antibody (ab87986) at 1 µg/mL

All lanes:

Human Plasma Total Protein Lysate at 10 µg

Secondary

All lanes:

Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution

Predicted band size: 77 kDa

Observed band size: 88 kDa

true

Exposure time: 3min

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

style

left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1 µg/mL", "WB-species-notes": "<p></p>" } } }

style

left-column

style

left-column

Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Storage buffer

pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

style

left-column

style

left-column

style

left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

style

left-column

Target data

C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4. Cleaves also IGFBP5 and thereby inhibits the trophic effects of IGF1.

See full target information C1S

style

left-column

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Blood 123:4015-22 PubMed24695853

2014

TNT003, an inhibitor of the serine protease C1s, prevents complement activation induced by cold agglutinins.

Applications

Unspecified application

Species

Unspecified reactive species

Ju Shi,Eileen L Rose,Andrew Singh,Sami Hussain,Nancy E Stagliano,Graham C Parry,Sandip Panicker

View all publications

style

left-column

style

left-column

style

right-column