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AB17452

Anti-C2 antibody [6E3]

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(1 Publication)

Mouse Monoclonal C2 antibody. Suitable for ELISA, WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Native Full Length Protein corresponding to Human C2.

View Alternative Names

Complement C2, C3/C5 convertase, C2

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

6E3

Isotype

IgG1

Light chain type

kappa

Carrier free

No

Reacts with

Human

Applications

WB, ELISA

applications

Immunogen

Native Full Length Protein corresponding to Human C2.

P06681

Epitope

Epitope specificity differs from that of ab17451 as determined by inhibition ELISA.

Specificity

Strong reaction is seen with human serum/plasma and no reaction is seen with serum from patients deficient in C2. ab17452 reacts with C2 and a subfraction of C2 believed to be C2b.

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Alternative Products

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Primary Antibodies

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Complementary Products

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Primary Antibodies

AB309149

Anti-Complement factor B antibody [EPR27443-6]

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Primary Antibodies

AB129059

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Secondary Antibodies

AB150077

Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488)

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Primary Antibodies

AB275931

Anti-C5 / C5b antibody [EPR23940-3]

20ul selling size|BOND RX™ Validated|KO Validated|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C5 / C5b antibody [EPR23940-3] (AB275931)

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p></p>", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein G
Storage buffer
pH: 7.4 Preservative: 0.097% Sodium azide Constituents: PBS, 2.9% Sodium chloride
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments : C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase.
See full target information C2
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

BMC immunology 11:43 PubMed20727163

2010

Recombinant human complement component C2 produced in a human cell line restores the classical complement pathway activity in-vitro: an alternative treatment for C2 deficiency diseases.

Applications

sELISA

Species

Human

Paolo G V Martini,Lynette C Cook,Scott Alderucci,Angela W Norton,Dianna M Lundberg,Susan M Fish,Knut Langsetmo,Göran Jönsson,Christian Lood,Birgitta Gullstrand,Kate J Zaleski,Nancy Savioli,Jason Lottherand,Charles Bedard,John Gill,Michael F Concino,Michael W Heartlein,Lennart Truedsson,Jan L Powell,Arthur O Tzianabos
View all publications
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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