AB240966

Anti-C2orf69 antibody [EPR13713] - BSA and Azide free

RabMAb
Recombinant
What is this?

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(1 Publication)

Rabbit Recombinant Monoclonal C2orf69 antibody. Carrier free. Suitable for WB and reacts with Human samples. Cited in 1 publication.

View Alternative Names

Mitochondrial protein C2orf69, C2orf69

1 Images

Supplier Data

Western blot - Anti-C2orf69 antibody [EPR13713] - BSA and Azide free (AB240966)

This data was developed using the same antibody clone in a different buffer formulation containing PBS, BSA, glycerol, and sodium azide (ab188870).

All lanes:

Western blot - Anti-C2orf69 antibody [EPR13713] (<a href='/en-us/products/primary-antibodies/c2orf69-antibody-epr13713-ab188870'>ab188870</a>) at 1/1000 dilution

Lane 1:

Human stomach lysate at 20 µg

Lane 2:

U87-MG lysate at 20 µg

Lane 3:

HeLa lysate at 20 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution

Predicted band size: 43 kDa

false

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR13713

Isotype

IgG

Carrier free

Yes

Reacts with

Human

Applications

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>" } } }

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Product details

ab240966 is the carrier-free version of ab188870.

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.

Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

Compatibility
This product is compatible with the Maxpar^® Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar^® is a trademark of Fluidigm Canada Inc.

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein A

Storage buffer

pH: 7.2 - 7.4 Constituents: PBS

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

+4°C

Storage information

Do Not Freeze

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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

C2orf69 also known as Chromosome 2 open reading frame 69 is a protein involved in specific cellular functions though the mechanical details remain not completely understood. The molecular mass of C2orf69 is approximately 46 kDa. It shows expression in multiple human tissues with notable presence in the brain and liver. This suggests its involvement in diverse biological processes.

Biological function summary

The C2orf69 protein appears implicated in cellular metabolic pathways contributing to energy production and cellular homeostasis. It potentially integrates into larger multi-protein complexes assisting in the regulation of metabolic flow. Its role in such processes emphasizes its importance in normal cell function and growth.

Pathways

C2orf69 interacts within energy metabolism and mitochondrial function pathways. It may interact with proteins important to these pathways such as those involved in respiratory chain and ATP synthesis. Understanding these interactions helps in deciphering C2orf69’s contribution to cellular metabolism and might provide insights into broader biological mechanisms.

C2orf69 associates with mitochondrial dysfunction and metabolic disorders like Leigh Syndrome and other neurodegenerative diseases. These conditions often involve disruptions in proteins such as NDUFS1 or other complex I components. Connections of C2orf69 with these proteins and diseases highlight potential targets for therapeutic intervention and warrant further investigation into its exact pathological role.

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

May play a role in the respiratory chain.

See full target information C2orf69

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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Molecular medicine reports 21:2209-2219 PubMed32186759

2020

PDGFD induces ibrutinib resistance of diffuse large B‑cell lymphoma through activation of EGFR.

Applications

Unspecified application

Species

Unspecified reactive species

Jia Jin,Leiping Wang,Zhonghua Tao,Jian Zhang,Fangfang Lv,Junning Cao,Xichun Hu

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-C2orf69 antibody [EPR13713] - BSA and Azide free

Western blot - Anti-C2orf69 antibody [EPR13713] - BSA and Azide free (AB240966)

Key facts

Host species

Clonality

Clone number

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Product details

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Storage information

Supplementary information

Biological function summary

Pathways

Product protocols

Target data

Publications (1)

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Product promise