Rabbit Polyclonal C3Orf34 antibody. Suitable for ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human CEP19 aa 50 to C-terminus.
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C3orf34, HSD5, CEP19, Centrosomal protein of 19 kDa, Cep19
- ICC/IF
Supplier Data
Immunocytochemistry/ Immunofluorescence - Anti-C3Orf34 antibody (AB221816)
PFA-fixed, Triton X-100 permeabilized U-2 OS (human bone osteosarcoma epithelial cell line) cells stained for C3Orf34 (green) using ab221816 at 4 μg/ml in ICC/IF.
Reactivity data
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Biological function summary
C3Orf34 engages in critical cellular processes influencing cell growth and survival. It becomes part of multiprotein complexes essential for metabolite processing and energy distribution. Interaction within these complexes helps stabilize protein structures and allows effective metabolic flux. Researchers have found that C3Orf34 impacts cellular responses to metabolic stress thereby affecting how cells adapt to changes in their environment. Through these activities it contributes not only to regular cellular functions but also to overarching physiological processes.
Pathways
C3Orf34 participates in the central metabolic and signal transduction pathways including the glycolysis and AMPK pathways. The glycolytic pathway involves C3Orf34 in the process of breaking down glucose for energy while the AMPK pathway relies on its role in energy sensing and homeostasis. In these pathways C3Orf34 interacts with key proteins such as AMPK itself and enzymes involved in metabolic regulation. These interactions highlight its place in controlling metabolic rates adapting to energy demands and ensuring cellular energy balance.
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Publications (1)
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Proceedings of the National Academy of Sciences of the United States of America 121:e2404243121 PubMed39331410
2024
Applications
Unspecified application
Species
Unspecified reactive species
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