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AB230681

Anti-C3orf43 antibody [1H6]

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(1 Publication)

Mouse Monoclonal C3orf43 antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human SMCO1.

View Alternative Names

C3orf43, SMCO1, Single-pass membrane and coiled-coil domain-containing protein 1, Single-pass membrane protein with coiled-coil domains 1

3 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C3orf43 antibody [1H6] (AB230681)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C3orf43 antibody [1H6] (AB230681)

Formalin-fixed, paraffin-embedded human skeletal muscle tissue stained for C3orf43 using ab230681 at 10 μg/ml in immunohistochemical analysis.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C3orf43 antibody [1H6] (AB230681)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C3orf43 antibody [1H6] (AB230681)

Formalin-fixed, paraffin-embedded human lung tissue stained for C3orf43 using ab230681 at 10 μg/ml in immunohistochemical analysis.

Western blot - Anti-C3orf43 antibody [1H6] (AB230681)
  • WB

Supplier Data

Western blot - Anti-C3orf43 antibody [1H6] (AB230681)

All lanes:

Western blot - Anti-C3orf43 antibody [1H6] (ab230681) at 1/2000 dilution

Lane 1:

HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) (transfected with empty vector) cell lysate at 5 µg

Lane 2:

C3orf43-transfected HEK-293T cell lysate at 5 µg

Predicted band size: 25 kDa

false

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

1H6

Isotype

IgG1

Carrier free

No

Reacts with

Human

Applications

IHC-P, WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Human SMCO1.

Q147U7

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/2000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "10 µg/mL", "IHCP-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Purification notes
Purified from TCS.
Storage buffer
Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 1% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

C3orf43 also known as Chromosome 3 open reading frame 43 represents a protein of interest in various cellular studies. The protein has an approximate mass of 27 kDa. Researchers observe its expression in multiple tissues indicating diverse functional roles within the body. The detailed mechanical function of C3orf43 remains under investigation but its ubiquitous presence highlights its potential importance in various cellular mechanisms.
Biological function summary

C3orf43 contributes to fundamental cellular processes without currently known participation in any large protein complex. It appears to play a role in specific cellular mechanisms potentially impacting cell signaling and regulation. Variability in its expression suggests that it might have adaptable functions depending on cellular context and environmental factors.

Pathways

Studies explore C3orf43 in the context of significant biological pathways such as the cell cycle and cellular stress response. These pathways involve interactions with proteins like CDK1 and HSP family proteins. Such interplay points to potential roles for C3orf43 in cell division regulation and cellular adaptation to stressors.

Research connects C3orf43 to conditions such as cancer and neurodegenerative diseases. Aberrant expression of C3orf43 links to tumorigenesis potentially interacting with proteins like TP53 in cancer pathways. In neurodegenerative conditions its interactions with proteins involved in cellular stress responses suggest implications in disease development or progression.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

See full target information SMCO1
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Journal of orthopaedic surgery and research 20:124 PubMed39891119

2025

Inhibition of id-1 reduces osteosarcoma growth and metastasis through mediation of snail.

Applications

Unspecified application

Species

Unspecified reactive species

Rongbing Shu,Zhuanyi Yu,Jianmin Wu,Qiuxin Cheng,Zhihao Peng,Huaqiang Zhou,Min Zhao
View all publications
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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