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Rabbit Polyclonal C5orf24 antibody. Suitable for WB, IHC-P and reacts with Mouse, Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human UPF0461 protein C5orf24 aa 1 to C-terminus.

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Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C5orf24 antibody (AB235404), expandable thumbnail
  • Western blot - Anti-C5orf24 antibody (AB235404), expandable thumbnail

Key facts

Isotype
IgG
Host species
Rabbit
Storage buffer

pH: 7.4
Preservative: 0.03% Proclin 300
Constituents: PBS, 50% Glycerol (glycerin, glycerine)

Form
Liquid
Clonality
Polyclonal

Immunogen

  • Recombinant Fragment Protein within Human UPF0461 protein C5orf24 aa 1 to C-terminus. The exact immunogen used to generate this antibody is proprietary information. Database link Q7Z6I8

Reactivity data

Select an application
Product promiseTestedExpectedPredictedNot recommended
WBIHC-P
Human
Expected
Tested
Mouse
Tested
Expected
Cow
Predicted
Predicted

Tested
Tested

Species
Mouse
Dilution info
1/1000.00000 - 1/5000.00000
Notes

-

Expected
Expected

Species
Human
Dilution info
Use at an assay dependent concentration.
Notes

-

Predicted
Predicted

Species
Cow
Dilution info
-
Notes

-

Tested
Tested

Species
Human
Dilution info
1/20.00000 - 1/200.00000
Notes

-

Expected
Expected

Species
Mouse
Dilution info
Use at an assay dependent concentration.
Notes

-

Predicted
Predicted

Species
Cow
Dilution info
-
Notes

-

Alternative names

Recommended products

Rabbit Polyclonal C5orf24 antibody. Suitable for WB, IHC-P and reacts with Mouse, Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human UPF0461 protein C5orf24 aa 1 to C-terminus.

Key facts

Isotype
IgG
Form
Liquid
Clonality
Polyclonal
Immunogen
  • Recombinant Fragment Protein within Human UPF0461 protein C5orf24 aa 1 to C-terminus. The exact immunogen used to generate this antibody is proprietary information. Database link Q7Z6I8
Purification technique
Affinity purification Protein G
Concentration
Loading...
Purification notes

Purity >95%

Storage

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Notes

Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.

If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.

Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.

Supplementary info

This supplementary information is collated from multiple sources and compiled automatically.
Activity summary

C5orf24 also known as Chromosome 5 open reading frame 24 is a protein with a molecular weight of approximately 54 kDa. This protein is expressed in various tissues but shows higher expression levels in the brain and liver suggesting its importance in these organs. The mechanical function of C5orf24 involves interactions with other cellular components though exact binding partners are still under investigation. Current research indicates potential involvement in cellular signaling or maintenance functions.

Biological function summary

The function of Chromosome 5 open reading frame 24 involves regulatory roles within the cell. Although not yet confirmed as part of a larger complex C5orf24 may participate in cellular processes such as proliferation and differentiation based on its expression pattern and interactions. These processes hint at a role in overall cellular health and development aligning with its presence in vital tissues like the brain and liver.

Pathways

Protein C5orf24 is implicated in essential signaling pathways including the PI3K/AKT pathway which influences cell survival and growth. This pathway is critical for transmitting signals from various growth factors and cytokines. Additionally C5orf24 might interact with proteins such as AKT and mTOR which are key players in cellular metabolism and growth regulation. This involvement in major pathways points to its potential as a modulatory protein within complex cellular networks.

Associated diseases and disorders

Research suggests that Chromosome 5 open reading frame 24 could have links to neurodegenerative diseases like Alzheimer's disease. Altered expression levels of C5orf24 in the brain may contribute to disease progression through its interaction with proteins such as Tau which is associated with neurofibrillary tangles. Furthermore C5orf24 may play a role in liver diseases possibly connected to disrupted cellular stress responses linking it with pathways involving proteins like ATF6 a regulator in the unfolded protein response.

Product promise

We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.

In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
Terms & Conditions.

2 product images

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C5orf24 antibody (ab235404), expandable thumbnail

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C5orf24 antibody (ab235404)

    Paraffin-embedded human kidney tissue stained for C5orf24 using ab235404 at 1/100 dilution in immunohistochemical analysis.

  • Western blot - Anti-C5orf24 antibody (ab235404), expandable thumbnail

    Western blot - Anti-C5orf24 antibody (ab235404)

    All lanes: Western blot - Anti-C5orf24 antibody (ab235404) at 1/1000 dilution

    Lane 1: Mouse gonadal tissue lysate

    Lane 2: K562 (human chronic myelogenous leukemia cell line from bone marrow) whole cell lysate

    Lane 3: THP-1 (human monocytic leukemia cell line) whole cell lysate

    Lane 4: U-87 MG (human glioblastoma-astrocytoma epithelial cell line) whole cell lysate

    Lane 5: HepG2 (human liver hepatocellular carcinoma cell line) whole cell lysate

    Lane 6: HeLa (human epithelial cell line from cervix adenocarcinoma) whole cell lysate

    Secondary

    All lanes: Goat polyclonal to Rabbit IgG at 1/10000 dilution

    Predicted band size: 20 kDa

Downloads

Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

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