Rabbit Polyclonal C5orf24 antibody. Suitable for WB, IHC-P and reacts with Mouse, Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human UPF0461 protein C5orf24 aa 1 to C-terminus.
pH: 7.4
Preservative: 0.03% Proclin 300
Constituents: PBS, 50% Glycerol (glycerin, glycerine)
WB | IHC-P | |
---|---|---|
Human | Expected | Tested |
Mouse | Tested | Expected |
Cow | Predicted | Predicted |
Species | Dilution info | Notes |
---|---|---|
Species Mouse | Dilution info 1/1000.00000 - 1/5000.00000 | Notes - |
Species | Dilution info | Notes |
---|---|---|
Species Human | Dilution info Use at an assay dependent concentration. | Notes - |
Species | Dilution info | Notes |
---|---|---|
Species Cow | Dilution info - | Notes - |
Species | Dilution info | Notes |
---|---|---|
Species Human | Dilution info 1/20.00000 - 1/200.00000 | Notes - |
Species | Dilution info | Notes |
---|---|---|
Species Mouse | Dilution info Use at an assay dependent concentration. | Notes - |
Species | Dilution info | Notes |
---|---|---|
Species Cow | Dilution info - | Notes - |
UPF0461 protein C5orf24, C5orf24
Rabbit Polyclonal C5orf24 antibody. Suitable for WB, IHC-P and reacts with Mouse, Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human UPF0461 protein C5orf24 aa 1 to C-terminus.
pH: 7.4
Preservative: 0.03% Proclin 300
Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Purity >95%
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C5orf24 also known as Chromosome 5 open reading frame 24 is a protein with a molecular weight of approximately 54 kDa. This protein is expressed in various tissues but shows higher expression levels in the brain and liver suggesting its importance in these organs. The mechanical function of C5orf24 involves interactions with other cellular components though exact binding partners are still under investigation. Current research indicates potential involvement in cellular signaling or maintenance functions.
The function of Chromosome 5 open reading frame 24 involves regulatory roles within the cell. Although not yet confirmed as part of a larger complex C5orf24 may participate in cellular processes such as proliferation and differentiation based on its expression pattern and interactions. These processes hint at a role in overall cellular health and development aligning with its presence in vital tissues like the brain and liver.
Protein C5orf24 is implicated in essential signaling pathways including the PI3K/AKT pathway which influences cell survival and growth. This pathway is critical for transmitting signals from various growth factors and cytokines. Additionally C5orf24 might interact with proteins such as AKT and mTOR which are key players in cellular metabolism and growth regulation. This involvement in major pathways points to its potential as a modulatory protein within complex cellular networks.
Research suggests that Chromosome 5 open reading frame 24 could have links to neurodegenerative diseases like Alzheimer's disease. Altered expression levels of C5orf24 in the brain may contribute to disease progression through its interaction with proteins such as Tau which is associated with neurofibrillary tangles. Furthermore C5orf24 may play a role in liver diseases possibly connected to disrupted cellular stress responses linking it with pathways involving proteins like ATF6 a regulator in the unfolded protein response.
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This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
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Terms & Conditions.
Paraffin-embedded human kidney tissue stained for C5orf24 using ab235404 at 1/100 dilution in immunohistochemical analysis.
All lanes: Western blot - Anti-C5orf24 antibody (ab235404) at 1/1000 dilution
Lane 1: Mouse gonadal tissue lysate
Lane 2: K562 (human chronic myelogenous leukemia cell line from bone marrow) whole cell lysate
Lane 3: THP-1 (human monocytic leukemia cell line) whole cell lysate
Lane 4: U-87 MG (human glioblastoma-astrocytoma epithelial cell line) whole cell lysate
Lane 5: HepG2 (human liver hepatocellular carcinoma cell line) whole cell lysate
Lane 6: HeLa (human epithelial cell line from cervix adenocarcinoma) whole cell lysate
All lanes: Goat polyclonal to Rabbit IgG at 1/10000 dilution
Predicted band size: 20 kDa
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