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AB222839

Anti-C6ORF10 antibody

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(1 Publication)

Rabbit Polyclonal C6ORF10 antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Mouse, Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human TSBP1 aa 200-500.

View Alternative Names

C6orf10, TSBP1, Testis-expressed basic protein 1, Uncharacterized protein C6orf10

4 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C6ORF10 antibody (AB222839)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C6ORF10 antibody (AB222839)

Paraffin-embedded human spleen tissue stained for C6ORF10 using ab222839 at 1/100 dilution in immunohistochemical analysis.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C6ORF10 antibody (AB222839)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C6ORF10 antibody (AB222839)

Paraffin-embedded human liver tissue stained for C6ORF10 using ab222839 at 1/100 dilution in immunohistochemical analysis.

Immunocytochemistry/ Immunofluorescence - Anti-C6ORF10 antibody (AB222839)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-C6ORF10 antibody (AB222839)

HepG2 (human liver hepatocellular carcinoma cell line) cells stained for C6ORF10 (green) using ab222839 at 1/100 dilution in ICC/IF. Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG (H+L) was used as secondary antibody.

Western blot - Anti-C6ORF10 antibody (AB222839)
  • WB

Supplier Data

Western blot - Anti-C6ORF10 antibody (AB222839)

All lanes:

Western blot - Anti-C6ORF10 antibody (ab222839) at 1/2000 dilution

All lanes:

mouse kidney tissue lysate

Secondary

All lanes:

Goat Anti-Rabbit IgG at 1/50000 dilution

Predicted band size: 61 kDa

Observed band size: 62 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse, Human

Applications

WB, ICC/IF, IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human TSBP1 aa 200-500. The exact immunogen used to generate this antibody is proprietary information.

Q5SRN2

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/200", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/50 - 1/200", "ICCIF-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/2000 - 1/5000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein G
Purification notes
Purity >95%
Storage buffer
pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

C6ORF10 also known as Chromosome 6 Open Reading Frame 10 is a protein whose function remains largely uncharacterized. It has an approximate molecular mass of 24 kDa. This protein exhibits expression in various tissues with noteworthy levels in immune-related organs such as the spleen and lymph nodes. Despite lacking a detailed functional profile studies suggest its involvement in immune system processes.
Biological function summary

C6ORF10 appears to play a role in cellular immune responses. It is associated with a complex known to include several proteins involved in immune regulation though specific components of this complex largely remain under investigation. This suggests that C6ORF10 might assist in signaling or regulatory roles within some immune pathways.

Pathways

C6ORF10 may participate in the antigen processing and presentation pathway a critical element of the immune response. It seems to work alongside other proteins like MHC class I molecules in presenting antigens to the immune system. Furthermore it may also have connections to the interferon signaling pathway collaborating with proteins such as STAT1 to modulate responses to pathogens.

C6ORF10 shows potential links to autoimmune diseases like rheumatoid arthritis. Malfunction or dysregulation of C6ORF10 in conjunction with proteins such as interleukin-6 could contribute to inflammatory processes central to the disease's pathology. Additionally preliminary evidence also suggests a possible involvement in certain cancer types wherein its role in immune modulation may impact tumor immunity dynamics.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

See full target information TSBP1
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

eLife 10: PubMed33491649

2021

TRIM37 prevents formation of centriolar protein assemblies by regulating Centrobin.

Applications

Unspecified application

Species

Unspecified reactive species

Fernando R Balestra,Andrés Domínguez-Calvo,Benita Wolf,Coralie Busso,Alizée Buff,Tessa Averink,Marita Lipsanen-Nyman,Pablo Huertas,Rosa M Ríos,Pierre Gönczy
View all publications
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